Evidence map›Paper›PMID 32192916›Full record

ReviewRedox biology2020

Redox basis of exercise physiology.

N V Margaritelis, V Paschalis, A A Theodorou, A Kyparos, M G Nikolaidis

Open access · goldAbstract readReview
In one paragraph

Review in Redox biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 2 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 2 syntheses or guidelines pooled it, 118 citations in OpenAlex.

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  16. Proteoforms as the true units of physiological function.European journal of applied physiology · 2026
    Review
  17. Review
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  19. Article
  20. Tart Cherry (International journal of molecular sciences · 2025
    Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

N V MargaritelisDepartment of Physical Education and Sport Science at Serres, Aristotle University of Thessaloniki, Thessaloniki, Greece; Dialysis Unit, 424 General Military Hospital of Thessaloniki, Thessaloniki, Greece. Electronic address: nvmargar@auth.gr.
V PaschalisSchool of Physical Education and Sport Science, National and Kapodistrian University of Athens, Athens, Greece.
A A TheodorouDepartment of Life Sciences, School of Sciences, European University Cyprus, Nicosia, Cyprus.
A KyparosDepartment of Physical Education and Sport Science at Serres, Aristotle University of Thessaloniki, Thessaloniki, Greece.
M G NikolaidisDepartment of Physical Education and Sport Science at Serres, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: nikolaidis@auth.gr.
Aristotle University of Thessaloniki · GREuropean University Cyprus · CYNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Redox reactions control fundamental processes of human biology. Therefore, it is safe to assume that the responses and adaptations to exercise are, at least in part, mediated by redox reactions. In this review, we are trying to show that redox reactions are the basis of exercise physiology by outlining the redox signaling pathways that regulate four characteristic acute exercise-induced responses (muscle contractile function, glucose uptake, blood flow and bioenergetics) and four chronic exercise-induced adaptations (mitochondrial biogenesis, muscle hypertrophy, angiogenesis and redox homeostasis). Based on our analysis, we argue that redox regulation should be acknowledged as central to exercise physiology.

Indexed as

ExerciseOrganelle BiogenesisAdaptation, PhysiologicalHumansMuscle ContractionMuscle, SkeletalOxidation-ReductionAdaptationsAntioxidantsExerciseRedox biologyResponsesSignaling

Identifiers

PMID32192916
PMCPMC7284946
OpenAlexW3011051047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.