ArticleBMC veterinary research2020
Management of otitis externa with an led-illuminated gel: a randomized controlled clinical trial in dogs.
Article in BMC veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- An Open-Label Split-Body Clinical Trial Evaluating Therapeutic Efficacy and Safety of Cold Atmospheric Plasma in Canine Acute Otitis Externa.Veterinary dermatology · 2026Article
- Evaluation of Dual-Near-Infrared-Wavelength Photobiomodulation Therapy for the Treatment of Canine Otitis Externa: A Prospective Multicenter Pilot Study.Animals : an open access journal from MDPI · 2026Article
- Effect of Fluorescence Photobiomodulation on Canine Progenitor Epidermal Keratinocytes With and Without Staphylococcus pseudintermedius Colonisation.Veterinary dermatology · 2026Article
- Long-term management of recurrent otitis externa in dogs using a two-phase protocol involving ciprofloxacin-clotrimazole-betamethasone and topical hydrocortisone aceponate.BMC veterinary research · 2026Article
- Effect of fluorescence biomodulation as an adjunct to standard wound management in open wounds in dogs and cats: a prospective, randomised, within-wound controlled clinical trial.Frontiers in veterinary science · 2026Article
- Evaluating the Antimicrobial and Antibiofilm Efficacy of Lavender Essential Oil and Linalool on Dual Candida albicans Biofilms With Staphylococcus aureus and Staphylococcus epidermidis From Canine External Otitis.Veterinary medicine and science · 2025Article
- Antibacterial effects of chitosan-based hydrogels containing Trachyspermum ammi essential oil on pathogens isolated from dogs with otitis externa.BMC veterinary research · 2024Article
- Exploring fluorescent light energy as management option for canine superficial bacterial folliculitis.Frontiers in veterinary science · 2023Article
- Critically Appraised Topic on Low-Level Laser Therapy (LLLT) in Dogs: An Advisable Treatment for Skin Diseases?Veterinary sciences · 2022Article
- Current Applications and Future Perspectives of Fluorescence Light Energy Biomodulation in Veterinary Medicine.Veterinary sciences · 2021Review
- The Effectiveness of Fluorescent Light Energy as Adjunct Therapy in Canine Deep Pyoderma: A Randomized Clinical Trial.Veterinary medicine international · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCanine otitis externa is a painful condition which can be challenging to treat due to difficulties in the administration of otic medication. This can be due to lack of owner compliance in the application of ear drops or due to the resentment that some dogs demonstrate when attempts are made to administer topical medication into a sensitive ear canal. The aim of the study was to assess the efficacy of a topical LED-illuminated gel (LIG) in canine otitis externa in comparison to standard of care therapy. Dogs with spontaneous otitis externa were randomly allocated in three groups: groups QW received LIG once weekly; BW received LIG twice weekly; group C received enrofloxacin and silver sulfadiazine twice daily. LIG consists of a topical application of a gel containing chromophores that, when illuminated by a LED lamp, re-emit fluorescent light which can stimulate physiological responses, promoting healing and controlling bacteria. The evaluation protocol (T
resultsAll groups (QW, n = 21; BW, n = 23; C, n = 20) showed improvement during the study (QW: P < 0.02 for cytological and pain scores, P < 0.003 for bacteriologic assessment, P < 10
conclusionsAll treatment groups showed a positive clinical effect. LIG administered twice-a-week was the most favourable protocol of the study. LIG may be considered beneficial in the management of canine otitis externa; it seems to be effective in controlling the clinical condition, including the signs of inflammation and local pain, the bacterial growth, and it may help increasing treatment compliance.
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