ArticleBMC geriatrics2020
Association between motoric cognitive risk syndrome and frailty among older Chinese adults.
Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Observational
- Clinical and neuroimaging correlates of motoric cognitive risk syndrome in cerebral small vessel disease: a cross-sectional study.Frontiers in aging neuroscience · 2026Article
- Dual decline in gait and cognition as a high-risk clinical phenotype: differential associations with cerebral amyloid-Frontiers in aging neuroscience · 2026Article
- Association of Motoric Cognitive Risk Syndrome and Its Components with Health Indicators in Community-dwelling Older Adults: A Cross-sectional Study.Progress in rehabilitation medicine · 2026Article
- Vitamin D, systemic inflammation, and motoric cognitive risk: exploring the risk factors and mediation pathways.Frontiers in aging · 2026Article
- From Dual Decline to Clinical Consequences: Mechanistic Pathways and Health Outcomes of Motoric Cognitive Risk Syndrome.Aging and disease · 2025Review
- Motoric Cognitive Risk Syndrome Associated With Risk of Frailty and Likelihood of Reversion in Older Adults.Journal of cachexia, sarcopenia and muscle · 2025Article
- Comparisons of four cognitive-frailty measures in predicting dementia and disability.BMC geriatrics · 2025Article
- Association of Motoric Cognitive Risk Syndrome and High C-Reactive Protein Serum Levels With Incident Major Neurocognitive Disorder: Results From the Quebec NuAge Cohort.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Observational
- Evaluation criteria for diagnosing motoric cognitive risk syndrome: a scoping review.Dementia & neuropsychologia · 2025Review
- Cardiometabolic and panvascular multimorbidity associated with motoric cognitive risk syndrome in older adults.Journal of geriatric cardiology : JGC · 2024Article
- Association of Motoric Cognitive Risk Syndrome with Sarcopenia and Systemic Inflammation in Pre-Frail Older Adults.Brain sciences · 2023Article
- Slow Gait, Subjective Cognitive Decline and Motoric Cognitive RISK Syndrome: Prevalence and Associated Factors in Community Dwelling Older Adults.The journal of nutrition, health & aging · 2021Article
- Motoric Cognitive Risk Syndrome: Symptoms, Pathology, Diagnosis, and Recovery.Frontiers in aging neuroscience · 2021Review
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMotoric cognitive risk syndrome (MCR) is a newly proposed predementia syndrome incorporating subjective cognitive complaints and slow gait. Previous studies have reported that subjective cognitive complaints and slow gait are associated with frailty in cognitively unimpaired older adults, but little is known about the link between MCR and frailty in older adults. Therefore, the aim of the study was to explore the associations of MCR and its components with frailty in older Chinese adults.
methodsIn an observational cross-sectional study, a total of 429 older adults aged 60 years and older were admitted to the geriatric department. According to MCR criteria, all participants were classified into 4 groups: 1) the MCR group; 2) the subjective cognitive complaints only group; 3) the slow gait only group; and 4) the healthy control group. Physical frailty was assessed by the Clinical Frailty Scale (CFS). Multivariate logistic regression analysis was used to examine the association between MCR and frailty in older adults.
resultsThe prevalence rates of subjective cognitive complaints, slow gait and MCR were 15.9, 10.0 and 4.0%, respectively. After adjusting for confounding variables, the logistic regression analysis showed that slow gait (odds ratio [OR]: 3.40, 95% confidence interval [CI]: 1.40-8.23, P = 0.007) and MCR (OR: 5.53, 95% CI: 1.46-20.89, P = 0.012) were independently associated with frailty, but subjective cognitive complaints were not.
conclusionsMCR and slow gait were significantly associated with frailty in older Chinese adults. Further studies should prospectively determine the causal relationship between MCR and frailty.
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