Evidence map›Paper›PMID 32192409›Full record

Observational studyJournal of the American Heart Association2020

Relationship Between Dietary Magnesium Intake and Incident Heart Failure Among Older Women: The WHI.

Wen-Chih Wu, Mengna Huang, Tracey H Taveira, Mary B Roberts, Lisa W Martin, Gregory A Wellenius, Karen C Johnson, JoAnn E Manson, Simin Liu, Charles B Eaton

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Magnesium Level and Related Factors in Type 2 Diabetes Mellitus: A Cross-Sectional StudyEndocrine, metabolic & immune disorders drug targets · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Wen-Chih WuDivision of Cardiology Veterans Affairs Medical Center & The Miriam Hospital Alpert Medical School Brown University Providence RI.
Mengna HuangChanning Division of Network Medicine Brigham and Women's Hospital Boston MA.
Tracey H TaveiraDivision of Cardiology Veterans Affairs Medical Center & The Miriam Hospital Alpert Medical School Brown University Providence RI.
Mary B RobertsCenter for Primary Care and Prevention and the Department of Family Medicine Memorial Hospital of Rhode Island Pawtucket RI.
Lisa W MartinDivision of Cardiology George Washington University School of Medicine and Health Sciences Washington DC.
Gregory A WelleniusDepartment of Epidemiology Brown University School of Public Health Providence RI.
Karen C JohnsonDepartment of Preventive Medicine University of Tennessee Health Science Center Memphis TN.
JoAnn E MansonBrigham and Women's Hospital Harvard Medical School Boston MA.
Simin LiuDepartment of Epidemiology Brown University School of Public Health Providence RI.
Charles B EatonCenter for Primary Care and Prevention and the Department of Family Medicine Memorial Hospital of Rhode Island Pawtucket RI.
Brown University · USBrigham and Women's Hospital · USGeorge Washington University · USMemorial Hospital of Rhode Island · USUniversity of Rhode Island · USUniversity of Tennessee Health Science Center · US

Funding

NHLBI NIH HHS HHSN268201600001CNHLBI NIH HHS HHSN268201600002CNHLBI NIH HHS HHSN268201600003CNHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS HHSN268201600018C
6 · The paper itself

Abstract

Background Women represent a large proportion of the growing heart failure (HF) epidemic, yet data are lacking regarding optimal dietary and lifestyle prevention strategies for them. Specifically, the association between magnesium intake and HF in a multiracial cohort of women is uncertain. Methods and Results We included 97 725 postmenopausal women from the WHI (Women's Health Initiative) observational studies and placebo arms of the hormone trial. Magnesium intake was measured at baseline by a 122-item validated food-frequency questionnaire and stratified into quartiles based on diet only, total intake (diet with supplements), and residual intake (calibration by total energy). Incident hospitalized HF (2153 events, median follow-up 8.1 years) was adjudicated by medical record abstraction. In Cox proportional hazards models, we evaluated the association between magnesium intake and HF adjusting for potential confounders. Analyses were repeated on a subcohort (n=18 745; median-follow-up, 13.2 years) for whom HF cases were subclassified into preserved ejection fraction (526 events), reduced ejection fraction (291 events) or unknown (168 events). Most women were white (85%) with a mean age of 63. Compared with the highest quartile of magnesium intake, women in the lowest quartile had an increased risk of incident HF, with adjusted hazard ratios of 1.32 (95% CI, 1.02-1.71) for diet only (

Indexed as

DietDietary SupplementsRecommended Dietary AllowancesAgedAge FactorsFemaleHeart Disease Risk FactorsHeart FailureHumansIncidenceMagnesiumMagnesium DeficiencyMiddle AgedPostmenopauseProspective StudiesRisk AssessmentMagnesiumheart failure with preserved ejection fractionheart failure with reduced ejection fractionresidual methodtotal magnesium

Identifiers

PMID32192409
PMCPMC7428611
OpenAlexW3012289666

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.