Evidence map›Paper›PMID 32192153›Full record

ArticleInternational journal of molecular sciences2020

Soluble Epoxide Hydrolase 2 Expression Is Elevated in Obese Humans and Decreased by Physical Activity.

Abdelkrim Khadir, Sina Kavalakatt, Dhanya Madhu, Preethi Cherian, Fahd Al-Mulla, Jehad Abubaker, Ali Tiss

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Abdelkrim KhadirBiochemistry and Molecular Biology Department, Research Division, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.
Sina KavalakattBiochemistry and Molecular Biology Department, Research Division, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.
Dhanya MadhuBiochemistry and Molecular Biology Department, Research Division, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.
Preethi CherianBiochemistry and Molecular Biology Department, Research Division, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.
Fahd Al-MullaResearch Division, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.ORCID 0000-0001-5409-3829
Jehad AbubakerBiochemistry and Molecular Biology Department, Research Division, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.
Ali TissBiochemistry and Molecular Biology Department, Research Division, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.
Dasman Diabetes Institute · KW

Funding

Kuwait Foundation for the Advancement of Sciences RA2010-003
6 · The paper itself

Abstract

Epoxide hydrolase 2 (EPHX2) is an emerging therapeutic target in several immunometabolic disorders. EPHX2 metabolizes anti-inflammatory epoxyeicosatrienoic acids into pro-inflammatory diols. The contribution of EPHX2 activity to human obesity remains unexplored. We compared the expression of EPHX2 between lean and obese humans (

Indexed as

ExerciseGene Expression RegulationAdultBiomarkersBody Weights and MeasuresEndoplasmic Reticulum Chaperone BiPEpoxide HydrolasesFemaleHumansLeukocytes, MononuclearMaleMiddle AgedObesityRNA, MessengerSubcutaneous FatBiomarkersEndoplasmic Reticulum Chaperone BiPEPHX2 protein, humanEpoxide HydrolasesHSPA5 protein, humanHspa5 protein, mouseRNA, MessengerdiabetesEPHX2exerciseobesitysEH

Identifiers

PMID32192153
PMCPMC7139757
OpenAlexW3011071628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.