Evidence map›Paper›PMID 32192122›Full record

ArticleMicroorganisms2020

Overexpression of Semaphorin 3A is a Marker Associated with Poor Prognosis in Patients with Nasopharyngeal Carcinoma.

Tomoko Imoto, Satoru Kondo, Naohiro Wakisaka, Pham Tahnh Hai, Noriko Seishima, Makoto Kano, Takayoshi Ueno, Harue Mizokami, Yosuke Nakanishi, Miyako Hatano and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. SEMAPHORINS and their receptors: focus on the crosstalk between melanoma and hypoxia.Journal of experimental & clinical cancer research : CR · 2021
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Tomoko ImotoDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Satoru KondoDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Naohiro WakisakaDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Pham Tahnh HaiDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Noriko SeishimaDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Makoto KanoDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Takayoshi UenoDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Harue MizokamiDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Yosuke NakanishiDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Miyako HatanoDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Kazuhira EndoDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Hisashi SugimotoDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Makiko Moriyama-KitaDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Tomokazu YoshizakiDivision of Otolaryngology and Head and Neck Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara, Kanazawa, Ishikawa 920-8641, Japan.
Kanazawa University · JP

Funding

Japan Society for the Promotion of Science JP16H05480Japan Society for the Promotion of Science JP17H01590
6 · The paper itself

Abstract

Semaphorins were discovered as guidance signals that mediate neural development. Recent studies suggest that semaphorin 3A (Sema3A), a member of the semaphorin family, is involved in the development of several cancers. This study aimed to analyze the association of Sema3A with the clinical features of nasopharyngeal carcinoma (NPC), an Epstein-Barr virus-associated carcinoma, and the Epstein-Barr virus primary oncogene latent membrane protein 1 (LMP1). The expression of Sema3A and LMP1 was immunohistochemically examined in the 35 NPC specimens. The mean expression scores for Sema3A and LMP1 were 20.8% ± 14.5% and 13.9% ± 14.8%, respectively. The expression of Sema3A significantly correlated with that of LMP1 (r = 0.41,

Indexed as

Epstein–Barr viruslatent membrane protein 1 (LMP1)nasopharyngeal carcinomaprognosissemaphorin

Identifiers

PMID32192122
PMCPMC7143379
OpenAlexW3010797625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.