ReviewPlants (Basel, Switzerland)2020
Impact of Spontaneous Haploid Genome Doubling in Maize Breeding.
Review in Plants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- A two-stage screening approach integrated with GWAS for rare phenotypes such as spontaneous haploid genome doubling in maize.Frontiers in plant science · 2026Article
- AutoSiQ: a curated haploidFrontiers in plant science · 2026Article
- Somatic genome doubling determines fertility in maize haploids of inbred A427.Frontiers in plant science · 2026Article
- Association mapping of haploid male fertility in sweet corn.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Dissecting the genetic variation of haploid frailty in maize for enhanced doubled haploid breeding.Frontiers in plant science · 2025Article
- Genome-wide association study of haploid female fertility (HFF) and haploid male fertility (HMF) in BS39-derived doubled haploid maize lines.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
- A novel in vivo genome editing doubled haploid system for Zea mays L.Nature plants · 2024Article
- Use of simulation to optimize a sweet corn breeding program: implementing genomic selection and doubled haploid technology.G3 (Bethesda, Md.) · 2024Article
- Fine mapping of major QTL qshgd1 for spontaneous haploid genome doubling in maize (Zea mays L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Haploid male fertility is restored by parallel spindle genes in Arabidopsis thaliana.Nature plants · 2023Article
- Overcoming roadblocks forFrontiers in plant science · 2023Review
- Maternal haploid waxy maize, environmental effects on grain yield, and quality parameters.PloS one · 2022Article
- Major locus for spontaneous haploid genome doubling detected by a case-control GWAS in exotic maize germplasm.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Diallelic Analysis of Tropical Maize Germplasm Response to Spontaneous Chromosomal Doubling.Plants (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Doubled haploid (DH) technology has changed the maize-breeding landscape in recent years. Traditionally, DH production requires the use of chemical doubling agents to induce haploid genome doubling and, subsequently, male fertility. These chemicals can be harmful to humans and the plants themselves, and typically result in a doubling rate of 10%-30%. Spontaneous genome doubling and male fertility of maize haploids, without using chemical doubling agents, have been observed to a limited extent, for nearly 70 years. Rates of spontaneous haploid genome doubling (SHGD) have ranged from less than 5% to greater than 50%. Recently, there has been increased interest to forgo chemical treatment and instead utilize this natural method of doubling. Genetic-mapping studies comprising worldwide germplasm have been conducted. Of particular interest has been the detection of large-effect quantitative trait loci (QTL) affecting SHGD. Having a single large-effect QTL with an additive nature provides flexibility for the method of introgression, such as marker-assisted backcrossing, marker-assisted gene pyramiding, and systematic design. Moreover, it allows implementation of new methodologies, such as haploid-inducer mediated genome editing (HI-edit) and promotion of alleles by genome editing. We believe the use of SHGD can further enhance the impact of DH technology in maize.
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Registered trials
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