Evidence map›Paper›PMID 32192052›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

In Vitro Anti-Prostate Cancer Activity of Two Ebselen Analogues.

Katarzyna B Kaczor-Keller, Anna Pawlik, Jacek Scianowski, Agata Pacuła, Magdalena Obieziurska, Fabio Marcheggiani, Ilenia Cirilli, Luca Tiano, Jedrzej Antosiewicz

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Current issues in molecular biology · 2024
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  2. Review
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  4. Influence of CeInternational journal of molecular sciences · 2021
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  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Katarzyna B Kaczor-KellerDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, 80-211 Gdansk, Poland.
Anna PawlikDepartment of Medical Biology and Genetics, University of Gdansk, 80-308 Gdansk, Poland.
Jacek ScianowskiDepartment of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 87-100 Torun, Poland.ORCID 0000-0002-3868-2022
Agata PacułaDepartment of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 87-100 Torun, Poland.
Magdalena ObieziurskaDepartment of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 87-100 Torun, Poland.
Fabio MarcheggianiDepartment of Life and Environmental Sciences, Polytechnic University of Marche, 60-100 Anconan, Italy.
Ilenia CirilliDepartment of Life and Environmental Sciences, Polytechnic University of Marche, 60-100 Anconan, Italy.ORCID 0000-0001-6916-5426
Luca TianoDepartment of Life and Environmental Sciences, Polytechnic University of Marche, 60-100 Anconan, Italy.
Jedrzej AntosiewiczDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, 80-211 Gdansk, Poland.ORCID 0000-0002-7871-6469
Gdańsk Medical University · PLNicolaus Copernicus University · PLStazione Zoologica Anton Dohrn · IT

Funding

Narodowe Centrum Nauki UMO- 2015/17/B/NZ7/03058
6 · The paper itself

Abstract

Scientific research has been underway for decades in order to develop an effective anticancer drug, and it has become crucial to find a novel and effective chemotherapeutics in the case of prostate cancer treatment. Ebselen derivatives have been shown to possess a variety of biological activities, including cytostatic and cytotoxic action against tumor cells. In this study, the cytotoxic effect and anticancer mechanism of action of two organoselenium compounds- (

Indexed as

apoptosis 2chemoprevention 5DNA damage 4Organoselenium compound 1ROS 3

Identifiers

PMID32192052
PMCPMC7151718
OpenAlexW3012497606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.