Evidence map›Paper›PMID 32192028›Full record

ArticleInternational journal of environmental research and public health2020

When Multiple Objective Measures of Medication Adherence Indicate Incongruent Adherence Results: An Example with Pediatric Cancer.

Caitlin J Cain, Andrea R Meisman, Kirstin Drucker, Evrosina I Isaac, Tanvi Verma, Jordyn Griffin, Jennifer M Rohan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Caitlin J CainChildren's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA 23219, USA.ORCID 0000-0003-4141-275X
Andrea R MeismanDivision of Adolescent and Transition Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Kirstin DruckerChildren's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA 23219, USA.
Evrosina I IsaacChildren's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA 23219, USA.
Tanvi VermaChildren's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA 23219, USA.
Jordyn GriffinChildren's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA 23219, USA.
Jennifer M RohanChildren's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA 23219, USA.
Virginia Commonwealth University · USCincinnati Children's Hospital Medical Center · USGeorgetown University · US

Funding

Promoting Treatment Adherence in Adolescent LeukemiaR01CA119162 · NCI · CINCINNATI CHILDRENS HOSP MED CTR · PI DROTAR, DENNIS D · 2007 to 2012
$3.3M
The Impact of Treatment Adherence on A Clinical Biomarker in Pediatric Acute LympF31CA168307 · NCI · UNIVERSITY OF CINCINNATI · PI ROHAN, JENNIFER MARIE · 2013 to 2014
$49k
NCI NIH HHS F31 CA168307NCI NIH HHS R01 CA119162
6 · The paper itself

Abstract

Previous research suggests that children and adolescents with acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) often have difficulty adhering to complex treatment regimens during the maintenance phase of therapy. Measurement of treatment adherence can be done via objective (e.g., electronic monitoring (EM), pharmacological assays) or subjective methods (patient, parent, or physician reports). This paper provides an illustration of recommended strategies for comparing discrepancies between two objective measures of medication adherence (e.g., behavioral adherence using electronic monitoring versus pharmacological adherence using 6-mercaptopurine (6MP) metabolite data) within a relatively large cohort of pediatric patients with ALL or LBL (

Indexed as

Medication AdherencePrecursor Cell Lymphoblastic Leukemia-LymphomaAdolescentChildCohort StudiesFemaleHumansMaleMercaptopurineMercaptopurineadherencecancerelectronic monitoringmetabolitespharmacology

Identifiers

PMID32192028
PMCPMC7142654
OpenAlexW3012116046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.