Evidence map›Paper›PMID 32191713›Full record

ArticlePloS one2020

Clinical correlates of sarcopenia and falls in Parkinson's disease.

Danielle Pessoa Lima, Samuel Brito de Almeida, Janine de Carvalho Bonfadini, João Rafael Gomes de Luna, Madeleine Sales de Alencar, Edilberto Barreira Pinheiro-Neto, Antonio Brazil Viana-Júnior, Samuel Ranieri Oliveira Veras, Manoel Alves Sobreira-Neto, Jarbas de Sá Roriz-Filho and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. The prevalence of sarcopenia in Parkinson's disease and related disorders- a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Frailty in Parkinson's disease: time to integrate it into treatment decision-making?Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  5. Article
  6. Review
  7. Metabolic profiles associated with fat loss in Parkinson's disease.Journal of neurology, neurosurgery, and psychiatry · 2026
    Article
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  12. Review
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  19. LRRK2Journal of cachexia, sarcopenia and muscle · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Danielle Pessoa LimaDivision of Neurology, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.ORCID 0000-0003-4591-727X
Samuel Brito de AlmeidaClinical Research Unit of Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, Brazil.
Janine de Carvalho BonfadiniDivision of Neurology, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.
João Rafael Gomes de LunaDivision of Geriatrics, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.
Madeleine Sales de AlencarDivision of Geriatrics, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.
Edilberto Barreira Pinheiro-NetoDivision of Geriatrics, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.
Antonio Brazil Viana-JúniorClinical Research Unit of Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, Brazil.
Samuel Ranieri Oliveira VerasDivision of Neurology, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.
Manoel Alves Sobreira-NetoDivision of Neurology, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.
Jarbas de Sá Roriz-FilhoDivision of Geriatrics, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.
Pedro Braga-NetoDivision of Neurology, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil.
Universidade Federal do Ceará · BRUniversidade Estadual do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia is a complex and multifactorial geriatric condition seen in several chronic degenerative diseases. This study aimed to screen for sarcopenia and fall risk in a sample of Parkinson's disease (PD) patients and to investigate demographic and clinical factors associated.

methodsThis is a cross-sectional study. We evaluated 218 PD patients at the Movement Disorders Clinic in Fortaleza, Brazil, and collected clinical data including experiencing falls in the six months prior to their medical visit. Probable sarcopenia diagnosis was confirmed by using a sarcopenia screening tool (SARC-F questionnaire) and the presence of low muscle strength.

resultsOne hundred and twenty-one patients (55.5%) were screened positive for sarcopenia using the SARC-F and 103 (47.4%) met the criteria for probable sarcopenia. Disease duration, modified Hoehn and Yahr stage, Schwab and England Activities of Daily Living Scale score, levodopa equivalent dose, probable sarcopenia and positive SARC-F screening were all associated with experiencing falls. Disease duration, lower quality of life and female gender were independently associated with sarcopenia. Experiencing falls was significantly more frequent among patients screened positive in the SARC-F compared to those screened negative.

conclusionsSarcopenia and PD share common pathways and may affect each other's prognosis and patients' quality of life. Since sarcopenia is associated with lower quality of life and increased risk of falls, active case finding, diagnosis and proper management of sarcopenia in PD patients is essential.

Indexed as

Quality of LifeAccidental FallsActivities of Daily LivingAgedBrazilCross-Sectional StudiesFemaleGeriatric AssessmentHand StrengthHumansMaleMiddle AgedParkinson DiseasePrognosisRisk FactorsSarcopenia

Identifiers

PMID32191713
PMCPMC7082018
OpenAlexW3011652880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.