Evidence map›Paper›PMID 32191649›Full record

ArticleActa bio-medica : Atenei Parmensis2020

Effects of D-Mannose, ElliroseTM and Lactobacillus Plantarum in treatment of urinary tract recurrent infections (rUTIs): A survey of urologists knowledge about its clinical application.

Riccardo Milandri, Tommaso Bocchialini, Matteo Maltagliati, Cotugno Michele, Elisa Simonetti, Ferretti Stefania, Umberto Vittorio Maestroni, Bernardo Maria Cesare Rocco, Salvatore Micali

Open access · greenAbstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Riccardo MilandriDepartment of Urology, University of Modena and Reggio Emilia, Modena, Italy. riccardomilandri85@gmail.com.
Tommaso BocchialiniDepartment of Urology, University of Modena and Reggio Emilia, Modena, Italy. tommaso.bocchialini@libero.it.
Matteo MaltagliatiDepartment of Urology, University of Modena and Reggio Emilia, Modena, Italy. matteo.maltagliati90@gmail.com.
Cotugno MicheleDepartment of Urology, University of Modena and Reggio Emilia, Modena, Italy. cotugnomichele25@gmail.com.
Elisa SimonettiDepartment of Urology, University of Modena and Reggio Emilia, Modena, Italy. elisasimonetti88@gmail.com.
Ferretti StefaniaU.O.C. of Urology, University-Hospital of Parma, Parma, Italy. sferretti@ao.pr.it.
Umberto Vittorio MaestroniU.O.C. of Urology, University-Hospital of Parma, Parma, Italy. umaestroni@ao.pr.it.
Bernardo Maria Cesare RoccoDepartment of Urology, University of Modena and Reggio Emilia, Modena, Italy. bernardo.rocco@gmail.com.
Salvatore MicaliDepartment of Urology, University of Modena and Reggio Emilia, Modena, Italy. salvatore.micali@unimore.it.
University of Modena and Reggio Emilia · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and aim of the workUrinary tract infections (UTIs) and recurrent urinary tract infections (rUTIs) are widespread disease and almost half of all women will experience at least one episode of cystitis during their life. Aim of this study was to review the evidence of literature about the therapeutic and preventive effects of a product containing D-Mannose, ElliroseTM and Lactobacollus Plantarum on patients' symptoms, quality of life and recurrence of UTIs and to investigate the practicing urologists' knowledge about the clinical application of this product. MATERIALS: We administrated an investigational survey about clinical use of a phytotherapeutic product made of D-Mannose, ElliroseTM and Lactobacollus Plantarum to 12 residents in Urology at the University of Modena and Reggio Emilia and to 32 urologists working in the provinces of Modena, Reggio Emilia and Parma.

results61% of physicians have diagnosed rUTIs in 3-6 patients during a month, and 7% of them in more than 6 patients during the same period of time. By these results rUTIs appear as common pathological conditions. 59% prescribed the product at least 1 time a month and 14% prescribed it more than 5 times. 43% administrated the product after out-patient invasive examinations as cistoscopy and urodynamic exam for UTIs prevention. 55% noticed a significant improvement in patient's QoL (Quality of Life) suffering from rUTIs. Furthermore 48% also reported a significant effect for the improvement of urinary symptoms of patients. No gastric or general side effects have been noticed during the administration period. Finally the cost of integrator has been reported affordable for the great majority of patients.

conclusionsMany studies in Literature have shown that D-Mannose and H. sabdariffa (ElliroseTM) reduce the risk of development of rUTIs opposing colonization and proliferation of uropathogenic bacteria in urinary tract. Our investigational survey about the administration of a phytotherapeutic product showed that this product is well-known and has a proved positive impact.

Indexed as

PhytotherapyUrologistsHibiscusHumansItalyLactiplantibacillus plantarumMannosePlant ExtractsPractice Patterns, Physicians'Quality of LifeReinfectionSurveys and QuestionnairesUrinary Tract InfectionsMannosePlant Extracts

Identifiers

PMID32191649
PMCPMC7569579
OpenAlexW3010739960

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.