ArticlePsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2020
Shared molecular genetic risk of alcohol dependence and posttraumatic stress disorder (PTSD).
Article in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Genetic correlation between smoking behavior and gastroesophageal reflux disease: insights from integrative multi-omics data.BMC genomics · 2024Pooled it
- Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders.Molecular psychiatry · 2023Pooled it
- Investigating the shared genetic architecture between schizophrenia and body mass index.Molecular psychiatry · 2023Pooled it
- Group cognitive behavioral therapy as an effective approach for patients with alcohol dependence: A perspective study.Medicine · 2022Trial
- Advancing models of PTSD-AUD comorbidity: protocol for a multimethod framework using genetics and ecological momentary assessment.European journal of psychotraumatology · 2026Article
- MDMA alters fear extinction, and reduces alcohol consumption in inbred alcohol preferring iP rats but not outbred Wistar rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Investigating PTSD, mental disorders, and suicide through self-comparison: a self-controlled case series study over two decades.Translational psychiatry · 2026Article
- Evaluation of a 20-Item Version of the Trauma-Related Drinking to Cope Questionnaire.Journal of clinical psychology · 2025Article
- What is the role of paternal genetic transmission on risk for PTSD and internalizing and externalizing disorders?Psychological medicine · 2025Article
- Assessing shared psychological constructs as risk factors in comorbid PTSD-AUD combat-exposed male veterans.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2025Article
- Disentangling the genetic overlap between ischemic stroke and obesity.Diabetology & metabolic syndrome · 2024Article
- Article
- Line- and sex-dependent effects of juvenile stress on contextual fear- and anxiety-related behavior in high- and low-alcohol-preferring mouse lines.Behavioural brain research · 2024Article
- Posttraumatic stress disorder and its cross-generational familial relationship with drug use disorder and alcohol use disorder: an extended Swedish adoption study.European journal of psychotraumatology · 2024Article
- Sex and Gender Differences in Co-Occurring Alcohol Use Disorder and PTSD.Current addiction reports · 2023Article
- Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes.Psychological medicine · 2023Article
- Genetic associations between alcohol phenotypes and life satisfaction: a genomic structural equation modelling approach.Scientific reports · 2023Article
- Phenome-wide Association Analysis of Substance Use Disorders in a Deeply Phenotyped Sample.Biological psychiatry · 2023Article
- Genetic Addiction Risk and Psychological Profiling Analyses for "Preaddiction" Severity Index.Journal of personalized medicine · 2022Article
- Conceptualizing traumatic stress and the structure of posttraumatic psychopathology through the lenses of RDoC and HiTOP.Clinical psychology review · 2022Review
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Abstract
Alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) frequently co-occur, highlighting the importance of understanding the etiology of these comorbid conditions. Although AUD and PTSD are moderately heritable with modest overlap in genetic risk as estimated from family studies, there has been a paucity of work using molecular genetic data to estimate shared genetic effects on these conditions. This study used large-scale genomewide molecular data to examine shared genetic risk for AUD, specifically alcohol dependence (AD), and PTSD through cross-trait linkage disequilibrium (LD) score regression (LDSC; also known as LDSR). Summary statistics came from the Psychiatric Genomics Consortium (PGC) PTSD Workgroup Freeze 2 European ancestry (EA) participants (
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