Evidence map›Paper›PMID 32190786›Full record

ArticleTranslational medicine of aging2019

DDS promotes longevity through a microbiome-mediated starvation signal.

Haeri Choi, Sung Chun Cho, Young Wan Ha, Billie Ocampo, Shirley Park, Shiwen Chen, Christopher F Bennett, Jeehae Han, Ryan Rossner, Jong-Sun Kang and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational medicine of aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Flavin-containing monooxygenase (FMO): Beyond xenobiotics.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Haeri ChoiDepartment of Obstetrics & Gynecology, Oregon Health and Science University, Portland, OR 97239 USA.
Sung Chun ChoWell Aging Research Center, Daegu Geongbuk Institute Science and Technology (DGIST), Daegu, 42988, South Korea.
Young Wan HaWell Aging Research Center, Samsung Advanced Institute of Technology (SAIT), Suwon, South Korea.
Billie OcampoDepartment of Pathology, University of Washington, Seattle, Washington, USA.
Shirley ParkDepartment of Pathology, University of Washington, Seattle, Washington, USA.
Shiwen ChenDepartment of Pathology, University of Washington, Seattle, Washington, USA.
Christopher F BennettDepartment of Pathology, University of Washington, Seattle, Washington, USA.
Jeehae HanDepartment of Pathology, University of Washington, Seattle, Washington, USA.
Ryan RossnerDepartment of Pathology, University of Washington, Seattle, Washington, USA.
Jong-Sun KangDepartment of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 16419, South Korea.
Yun-Ll LeeWell Aging Research Center, Daegu Geongbuk Institute Science and Technology (DGIST), Daegu, 42988, South Korea.
Sang Chul ParkWell Aging Research Center, Daegu Geongbuk Institute Science and Technology (DGIST), Daegu, 42988, South Korea.
Matt KaeberleinDepartment of Pathology, University of Washington, Seattle, Washington, USA.
University of Washington · USDaegu Gyeongbuk Institute of Science and Technology · KRChonnam National University · KROregon Health & Science University · USSamsung (South Korea) · KRSungkyunkwan University · KR

Funding

SPECIFICITY OF OXYGEN DNA DAMAGE AND MUTAGENESISP01AG001751 · NIA · UNIVERSITY OF WASHINGTON · PI PRUSKY, GLEN THOMAS · 1985 to 2021
$29.6M
University of Washington Nathan Shock Center of Excellence in the Basic Biology of AgingP30AG013280 · NIA · UNIVERSITY OF WASHINGTON · PI Maitreya J Dunham · 1995 to 2026
$27.1M
GENETIC APPROACHES TO AGING RESEARCHT32AG000057 · NIA · UNIVERSITY OF WASHINGTON · PI RABINOVITCH, PETER S · 1985 to 2019
$14.2M
Environmetal Pathology/Toxicology Training ProgramT32ES007032 · NIEHS · UNIVERSITY OF WASHINGTON · PI FAUSTMAN, ELAINE M, ROSENFELD, MICHAEL E · 1985 to 2023
$10.7M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIA NIH HHS P01 AG001751NIA NIH HHS P30 AG013280NIA NIH HHS T32 AG000057NIEHS NIH HHS T32 ES007032NIH HHS P40 OD010440
6 · The paper itself

Abstract

The antibiotic diaminodiphenyl sulfone (DDS) is used in combination with other antibiotics as a first line treatment for leprosy. DDS has been previously reported to extend lifespan in

Identifiers

PMID32190786
PMCPMC7080190
OpenAlexW2955939654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.