Evidence map›Paper›PMID 32190750›Full record

ArticlePhysics and imaging in radiation oncology2019

Combined morphologic and metabolic pipeline for Positron emission tomography/computed tomography based radiotherapy response evaluation in locally advanced pancreatic adenocarcinoma.

Yi Lao, John David, Arman Torosian, Veronica Placencio, Yalin Wang, Andrew Hendifar, Wensha Yang, Richard Tuli

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Imaging science and development in modern high-precision radiotherapy.Physics and imaging in radiation oncology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi LaoDepartment of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, USA.
John DavidDepartment of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, USA.
Arman TorosianDepartment of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, USA.
Veronica PlacencioDepartment of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, USA.
Yalin WangSchool of Computing, Informatics, Decision Systems and Engineering, Arizona State University, Tempe, AZ, USA.
Andrew HendifarDepartment of Surgery, Cedars-Sinai Medical Center, Los Angeles, USA.
Wensha YangDepartment of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, USA.
Richard TuliDepartment of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, USA.

Funding

Novel four dimensional magnetic resonance imaging to monitor pancreatic tumor infiltrating blood vessels and tumor response to chemoradiation therapyR21CA234637 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FAN, ZHAOYANG, YANG, WENSHA · 2019 to 2020
$413k
NCI NIH HHS R21 CA234637
6 · The paper itself

Abstract

background and purposeAdaptive radiation planning for pancreatic adenocarcinoma (PA) relies on accurate treatment response assessment, while traditional response evaluation criteria inefficiently characterize tumors with complex morphological features or intrinsically low metabolism. To better assess treatment response of PA, we quantify and compare regional morphological and metabolic features of the 3D pre- and post-radiation therapy (RT) tumor models. MATERIALS AND

methodsThirty-one PA patients with pre and post-RT Positron emission tomography/computed tomography (PET/CT) scans were evaluated. 3D meshes of pre- and post-RT tumors were generated and registered to establish vertex-wise correspondence. To assess tumor response, Mahalanobis distances (

resultsAmong all the imaging/physiological parameters,

conclusionsWe introduced a PET/CT-based novel morphologic and metabolic pipeline for response evaluation in locally advanced PA. The fused

Indexed as

Chemoradiotherapy (CRT)Pancreatic adenocarcinoma (PA)Positron emission tomography/computedRadiation therapy (RT)tomography (PET/CT)Treatment response

Identifiers

PMID32190750
PMCPMC7079767

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.