Evidence map›Paper›PMID 32190685›Full record

ArticleBioMed research international2020

Baseline Levels of Serum Progesterone and the First Trimester Pregnancy Outcome in Women with Threatened Abortion: A Retrospective Cohort Study.

Yongshi Deng, Chi Chen, Siyun Chen, Guanyan Mai, Xiuping Liao, He Tian, Wenli Liu, Shuling Ji, Ying Liu, Jie Gao and 1 more

Abstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yongshi DengThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, China.ORCID https://orcid.org/0000-0003-4331-335X
Chi ChenDepartment of Immunology and Microbiology, Guiyang College of Traditional Chinese Medicine, Guiyang 550000, China.
Siyun ChenThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, China.
Guanyan MaiThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, China.
Xiuping LiaoThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, China.
He TianThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, China.
Wenli LiuThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, China.
Shuling JiThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, China.
Ying LiuThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, China.
Jie GaoDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, China.ORCID https://orcid.org/0000-0001-6934-6163
Songping LuoDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, China.ORCID https://orcid.org/0000-0002-6804-4216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe relationship between serum progesterone and the first trimester pregnancy outcome of threatened abortion is still controversial. Therefore, we aimed to further study the association between these two parameters.

methodsThe present study is an observational retrospective cohort study. A total of 726 participants who had threatened abortion from a hospital in Guangdong, China, were included in this study from 17th August 2011 to 30th October 2018. The exposure variable and the outcome variable were serum progesterone measured at baseline and early pregnancy outcome, respectively. Covariates involved in this study included patients' basic demographics, obstetric history, and clinical information.

resultsA negative association and a saturation effect were detected between serum progesterone and the first trimester pregnancy outcome. When progesterone <90.62 nmol/L, an increase in 1 nmol/L of serum progesterone was associated with 3% decrease of the risk of miscarriage (OR: 0.97, 95% CI: 0.95-0.98).

conclusionThere was a greater risk of abortion when the serum progesterone level was less than 90.62 nmol/L. Our findings can better assist the clinician in understanding patients' conditions and making medical decisions.

Indexed as

Abortion, ThreatenedPregnancy Trimester, FirstAbortion, SpontaneousAdultChinaFemaleHumansOdds RatioPregnancyPregnancy OutcomeProgesteroneRetrospective StudiesWomenProgesterone

Identifiers

PMID32190685
PMCPMC7072098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.