ArticleBioMed research international2020
Feature of Heart Rate Variability and Metabolic Mechanism in Female College Students with Depression.
Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 26 citations in OpenAlex.
- Effects of binaural beat therapy with different frequencies on autonomic nervous system regulation among college students.BMC complementary medicine and therapies · 2025Article
- Heart rate variability versus visual analog scale for objective and subjective mental fatigue detection: A randomized controlled trial.PLOS mental health · 2025Article
- Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth.Cambridge prisms. Precision medicine · 2023Review
- Plasma metabolic disturbances during pregnancy and postpartum in women with depression.iScience · 2022Article
- Review
- Review
- Effects of aerobic exercise on cognitive function in adults with major depressive disorder: A systematic review and meta-analysis.International journal of clinical and health psychology : IJCHPArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo explore the effects of depression on cardiac autonomic nerve function and related metabolic pathways, the heart rate variability (HRV) and urinary differential metabolites were detected on the college students with depression.
methods12 female freshmen with depression were filtered by the Beck Depression Inventory (BDI-II) and Self-rating Depression Scale (SDS). By wearing an HRV monitoring system, time domain indexes and frequency domain indexes were measured over 24 hours. Liquid chromatography-mass spectrometry (LC-MS) was used to detect their urinary differential metabolites. Differential metabolites were identified by principal component analysis (PCA) and orthogonal projections to latent structures discriminant analysis (OPLS-DA). The metabolic pathways related to these differential metabolites were analyzed by the MetPA database.
resultsStress time was significantly increased, and recovery time was markedly decreased in the depression group compared with the control group (
conclusionSome autonomic nervous system disruption, high stress, and poor fatigue recovery were confirmed in college students with depression. The metabolic mechanism involved the disruption of coenzyme Q biosynthesis, glycine-serine-threonine metabolism, tyrosine metabolism, pyrimidine metabolism, and steroid metabolism under daily stress.
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