Evidence map›Paper›PMID 32190609›Full record

ArticleJournal of bone metabolism2020

Inhibitory Effect of

Keun Ha Park, Dong Ryun Gu, Min Seuk Kim, Seoung Hoon Lee

Abstract read
In one paragraph

Article in Journal of bone metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Oral treatment withFrontiers in veterinary science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Keun Ha ParkDepartment of Oral Microbiology and Immunology, College of Dentistry, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-9998-9706
Dong Ryun GuDepartment of Oral Microbiology and Immunology, College of Dentistry, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-2516-690X
Min Seuk KimDepartment of Oral Physiology, College of Dentistry, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0003-0071-0830
Seoung Hoon LeeDepartment of Oral Microbiology and Immunology, College of Dentistry, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-3488-8189
Wonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThe effect of extract of RMF (RMF-E) on receptor activator of nuclear factor-κB ligand (RANKL)-mediated osteoclastogenesis was examined by tartrate-resistant acid phosphatase (TRAP) staining, real-time polymerase chain reaction and western blot analysis. In addition, RANKL-induced Ca

resultsRMF-E remarkably inhibited TRAP

conclusionsRMF-E negatively regulates osteoclast differentiation and formation. These findings suggest the possibility of RMF-E as a traditional therapeutic agent against osteoclast-related bone disorders such as osteoporosis, rheumatoid arthritis, and periodontitis.

Indexed as

Bone diseasesCalcium signalingNFATc1OsteoclastsOsteogenesis

Identifiers

PMID32190609
PMCPMC7064362
OpenAlexW3009647502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.