Evidence map›Paper›PMID 32190437›Full record

ArticleCureus2020

Acute Myeloid Leukemia Presenting As Thrombotic Thrombocytopenic Purpura.

Michael P Kucharik, David Waldburg, Anitha Chandran, Alison Kohn, Roozbeh Nazarian

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael P KucharikInternal Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.
David WaldburgInternal Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.
Anitha ChandranInternal Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.
Alison KohnInternal Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.
Roozbeh NazarianInternal Medicine, Boca Raton Regional Hospital, Boca Raton, USA.
Florida Atlantic University · USBoca Raton Regional Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of acute myeloid leukemia (AML) with myelodysplasia-related changes that presented as thrombotic thrombocytopenic purpura (TTP). Our patient presented with the classic pentad of TTP symptoms: anemia, thrombocytopenia, fever, elevated creatinine, and altered mental status. After a failure to respond to plasmapheresis therapy, we proceeded with a bone marrow biopsy and fluorescent in situ hybridization, which supported formal diagnosis of AML with myelodysplasia-related changes. Our case is an extremely rare presentation of a rare condition, as there have been no reported cases of AML with myelodysplasia-related changes presenting as TTP.

Indexed as

acute myeloid leukemiaamlmicroangiopathic hemolytic anemiamyelodysplasticthrombocytopeniathrombotic thrombocytopenic purpurattp

Identifiers

PMID32190437
PMCPMC7057253
OpenAlexW3004989430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.