ArticleClinical and translational allergy2020
Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK outcomes.
Article in Clinical and translational allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- EFFICACY OF NASAL IRRIGATION WITH ISOTONIC AND HYPERTONIC SOLUTIONS AFTER ENDOSCOPIC SINUS SURGERY FOR CHRONIC RHINOSINUSITIS WITH NASAL POLYPOSIS.Acta clinica Croatica · 2025Trial
- Nasal saline irrigation with azelastine-fluticasone nasal spray in moderate-to-severe persistent allergic rhinitis: a randomized controlled trial.Frontiers in allergy · 2025Trial
- Efficacy of sodium hyaluronate in relieving nasal symptoms of children with intermittent allergic rhinitis: a randomized controlled trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Trial
- Efficacy and Safety of Sea Salt-Derived Physiological Saline Nasal Spray as Add-On Therapy in Patients with Acute Upper Respiratory Infection: A Multicenter Retrospective Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2021Trial
- Efficacy of hypertonic nasal spray with algae in rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Observational
- Concurrent validity, cut-offs and ability to change of patient-reported outcome measures for rhinitis and asthma in MASK-airClinical and translational allergy · 2024Article
- The effect of nasal douching by hypertonic 2.3 per cent sea water with algae extracts on the concentration of epidermal growth factor, transforming growth factor-α and interleukin-8 in nasal secretions of patients with nasal polyposis following endoscopic surgical treatment.The Journal of laryngology and otology · 2024Article
- Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: The ARIA-MASK-airClinical and translational allergy · 2023Article
- Self-Management in Allergic Rhinitis: Strategies, Outcomes and Integration into Clinical Care.Journal of asthma and allergy · 2023Review
- Real-world data using mHealth apps in rhinitis, rhinosinusitis and their multimorbidities.Clinical and translational allergy · 2022Article
- Mobile health app for monitoring allergic rhinitis and asthma in real life in Lithuanian MASK-air users.Clinical and translational allergy · 2022Article
- Digital Health Europe (DHE) Twinning on severe asthma-kick-off meeting report.Journal of thoracic disease · 2021Article
- The Nose as a Route for Therapy: Part 1. Pharmacotherapy.Frontiers in allergy · 2021Review
- Preparation and quality evaluation of a volatile oil microemulsion from Flos magnoliae and Centipeda minima.Molecular medicine reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNasal irrigations (NI) are increasingly used as an over-the-counter adjunctive treatment for allergic rhinitis (AR), but clinical studies on their effectiveness are limited.
methodsAn open-label, controlled, non-randomized, real-life study was conducted to evaluate the effectiveness of NI with a new hypertonic solution as add-on treatment for AR. Children and adolescents with AR were prescribed symptomatic treatment. The active group also received an additional sea-water NI solution supplemented with algae extracts. The primary endpoint was symptom control, assessed by the control of allergic rhinitis and asthma test (CARAT) questionnaires. Moreover, the MASK/Allergy Diary was used to track symptoms and daily medication use that were combined in a novel total symptom/medication score (TSMS).
resultsWe assessed 76 patients. Overall, there was a significant improvement of CARAT results (median Z-score change of 1.1 in the active/NI group vs. 0.4 in the control group;
conclusionAddition of NI with a sea-water solution to regular treatment improved AR symptom control. CARAT questionnaires and MASK application can be useful outcome tools in real-life studies.
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Registered trials
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