Evidence map›Paper›PMID 32190272›Full record

ArticleChemical science2020

Serum Raman spectroscopy as a diagnostic tool in patients with Huntington's disease.

Anna Huefner, Wei-Li Kuan, Sarah L Mason, Sumeet Mahajan, Roger A Barker

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Anna HuefnerDepartment of Chemistry , University of Cambridge , Lensfield Road , Cambridge , CB2 1WE , UK.
Wei-Li KuanJohn van Geest Centre for Brain Repair , the WT-MRC Cambridge Stem Cell Institute , University of Cambridge , Forvie Site, Robinson Way , Cambridge , CB2 0PY , UK . Email: rab46@cam.ac.uk.ORCID 0000-0002-0273-1320
Sarah L MasonJohn van Geest Centre for Brain Repair , the WT-MRC Cambridge Stem Cell Institute , University of Cambridge , Forvie Site, Robinson Way , Cambridge , CB2 0PY , UK . Email: rab46@cam.ac.uk.
Sumeet MahajanThe Institute for Life Sciences , the School of Chemistry , University of Southampton , Highfield Campus , Southampton , SO17 1BJ , UK . Email: s.mahajan@soton.ac.uk.ORCID 0000-0001-8923-6666
Roger A BarkerJohn van Geest Centre for Brain Repair , the WT-MRC Cambridge Stem Cell Institute , University of Cambridge , Forvie Site, Robinson Way , Cambridge , CB2 0PY , UK . Email: rab46@cam.ac.uk.ORCID 0000-0001-8843-7730
Wellcome/MRC Cambridge Stem Cell Institute · GBUniversity of Southampton · GB

Funding

Medical Research Council MR/R015724/1Medical Research Council MR/S005528/1Wellcome Trust
6 · The paper itself

Abstract

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by an abnormal CAG expansion in exon 1 of the huntingtin (

Identifiers

PMID32190272
PMCPMC7067270
OpenAlexW2984422141

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.