Evidence map›Paper›PMID 32190260›Full record

ArticleChemical science2020

Programmable dynamic covalent nanoparticle building blocks with complementary reactivity.

Nicolas Marro, Flavio Della Sala, Euan R Kay

Abstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Constitutionally Selective Dynamic Covalent Nanoparticle Assembly.Journal of the American Chemical Society · 2022
    Article
  5. Article
  6. Article
  7. Rapidly Adaptive All-covalent Nanoparticle Surface Engineering.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicolas MarroEaStCHEM School of Chemistry , University of St Andrews , North Haugh , St Andrews , KY16 9ST , UK . Email: ek28@st-andrews.ac.uk.
Flavio Della SalaEaStCHEM School of Chemistry , University of St Andrews , North Haugh , St Andrews , KY16 9ST , UK . Email: ek28@st-andrews.ac.uk.ORCID 0000-0002-6142-9869
Euan R KayEaStCHEM School of Chemistry , University of St Andrews , North Haugh , St Andrews , KY16 9ST , UK . Email: ek28@st-andrews.ac.uk.ORCID 0000-0001-8177-6393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle-based devices, materials and technologies will demand a new era of synthetic chemistry where predictive principles familiar in the molecular regime are extended to nanoscale building blocks. Typical covalent strategies for modifying nanoparticle-bound species rely on kinetically controlled reactions optimised for efficiency but with limited capacity for selective and divergent access to a range of product constitutions. In this work, monolayer-stabilized nanoparticles displaying complementary dynamic covalent hydrazone exchange reactivity undergo distinct chemospecific transformations by selecting appropriate combinations of 'nucleophilic' or 'electrophilic' nanoparticle-bound monolayers with nucleophilic or electrophilic molecular modifiers. Thermodynamically governed reactions allow modulation of product compositions, spanning mixed-ligand monolayers to exhaustive exchange. High-density nanoparticle-stabilizing monolayers facilitate

Identifiers

PMID32190260
PMCPMC7067244

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.