Evidence map›Paper›PMID 32190259›Full record

ArticleChemical science2020

Biosynthesis of plant tetrahydroisoquinoline alkaloids through an imine reductase route.

Lu Yang, Jinmei Zhu, Chenghai Sun, Zixin Deng, Xudong Qu

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 50 citations in OpenAlex.

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  12. Recent trends in biocatalysis.Chemical Society reviews · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lu YangState Key Laboratory of Microbial Metabolism , School of Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China . Email: quxd@whu.edu.cn.
Jinmei ZhuKey Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of Education , School of Pharmaceutical Sciences , Wuhan University , Wuhan 430071 , China.
Chenghai SunKey Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of Education , School of Pharmaceutical Sciences , Wuhan University , Wuhan 430071 , China.
Zixin DengState Key Laboratory of Microbial Metabolism , School of Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China . Email: quxd@whu.edu.cn.
Xudong QuState Key Laboratory of Microbial Metabolism , School of Life Sciences and Biotechnology , Shanghai Jiao Tong University , Shanghai 200240 , China . Email: quxd@whu.edu.cn.ORCID 0000-0002-3301-8536
Shanghai Jiao Tong University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report a biocatalytic approach to synthesize plant tetrahydroisoquinoline alkaloids (THIQAs) from dihydroisoquinoline (DHIQ) precursors using imine reductases and

Identifiers

PMID32190259
PMCPMC7067268
OpenAlexW2985112839

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.