Evidence map›Paper›PMID 32190219›Full record

ArticleGastroenterology and hepatology from bed to bench2020

SE translocation gene but not zinc finger or X-linked factor is down-regulated in gastric cancer.

Shiva Soleimani, Negin Nasim, Farbod Esfandi, Morteza Karimipoor, Vahid Kholghi-Oskooei, Maryam Naby Gol, Mohammad Taheri, Soudeh Ghafouri-Fard

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Gastroenterology and hepatology from bed to bench, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shiva SoleimaniGenIran Lab, Tashkhis Gene Pajohesh, Tehran, Iran.
Negin NasimGenIran Lab, Tashkhis Gene Pajohesh, Tehran, Iran.
Farbod EsfandiGenIran Lab, Tashkhis Gene Pajohesh, Tehran, Iran.
Morteza KarimipoorMolecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Vahid Kholghi-OskooeiDepartment of Laboratory Sciences, School of Paramedical Sciences, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
Maryam Naby GolStudent Research Committee, Qom University of Medical Sciences, Qom, Iran.
Mohammad TaheriUrogenital Stem Cell Research Center, Shahid Beheshti University of Medical Sickness, Tehran, Iran.
Soudeh Ghafouri-FardDepartment of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahid Beheshti University of Medical Sciences · IRBiotechnology Research Center · IRQom University of Medical Science and Health Services · IRTorbat Heydarieh University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe current study aimed to identify the expression levels of

backgroundSET has been first identified as a component of a fusion protein produced by chromosomal rearrangement in a patient with acute undifferentiated leukemia. Subsequently, multiple functions have been attributed to this gene in different disorders such as cancer and Alzheimer's disease. The expression of SET is regulated by ZFX, a transcription factor which has a potential role in gastric cancer.

methodsIn this case-control study, we evaluated the expression of

results

conclusionOverall, our results imply the role of SET1 in gastric cancer and potentially functional associations between this gene and ZFX in gastric tissues.

Indexed as

Gastric cancerSETSE TranslocationZFXZinc finger and X-linked factor

Identifiers

PMID32190219
PMCPMC7069543
OpenAlexW3005198517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.