Evidence map›Paper›PMID 32190178›Full record

ArticleOxidative medicine and cellular longevity2020

MicroRNA-103 Protects Coronary Artery Endothelial Cells against H

Yiran Wang, Xianjing Song, Zhibo Li, Ning Liu, Youyou Yan, Tianyi Li, Wei Sun, Yinuo Guan, Ming Li, Yibo Yang and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

  1. Role of miR-155 and miR-103 in Oxidative Stress in Cardiovascular Disease: A Narrative Review.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Autophagy and the pancreas: Healthy and disease states.Frontiers in cell and developmental biology · 2024
    Review
  7. Autophagy in Heart Failure: Insights into Mechanisms and Therapeutic Implications.Journal of cardiovascular development and disease · 2023
    Review
  8. Unbalanced Redox With Autophagy in Cardiovascular Disease.Journal of lipid and atherosclerosis · 2023
    Review
  9. The role of pyroptosis in inflammatory diseases.Frontiers in cell and developmental biology · 2023
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Regulation of Pyroptosis by ncRNA: A Novel Research Direction.Frontiers in cell and developmental biology · 2022
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yiran WangDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Xianjing SongDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Zhibo LiDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-4237-8613
Ning LiuDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Youyou YanDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Tianyi LiDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-6556-454X
Wei SunDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yinuo GuanDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Ming LiDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yibo YangDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Xingru YangDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Bin LiuDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0003-2017-2160
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial cell damage caused by oxidative stress is widely considered to be a triggering event in atherosclerosis (AS). However, the specific effect elicited by autophagy in endothelial cells undergoing oxidative stress remains controversial, especially during end-stage autophagy. The inhibition of end-stage autophagy has been reported to increase cell pyroptosis and contribute to endothelial damage. Several studies have shown that microRNA-103 is involved in end-stage autophagy; however, its specific mechanism of action is not yet characterized. In this study, we addressed the regulatory role of miR-103 in autophagy during oxidative stress of endothelial cells. Hydrogen peroxide (H

Indexed as

AutophagyCoronary VesselsCytoprotectionDown-RegulationEndothelial CellsHumansHydrogen PeroxideMembrane ProteinsMicroRNAsOxidative StressProto-Oncogene ProteinsPyroptosisBNIP3 protein, humanHydrogen PeroxideMembrane ProteinsMicroRNAsMIRN103 microRNA, humanProto-Oncogene Proteins

Identifiers

PMID32190178
PMCPMC7071805
OpenAlexW3009686839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.