Evidence map›Paper›PMID 32190151›Full record

ArticleArchives of medical science : AMS2020

MicroRNA-490-3p suppresses hepatocellular carcinoma cell proliferation and migration by targeting the aurora kinase A gene (

Hui Zhang, Junhui Bao, Shahe Zhao, Zhongchao Huo, Baowei Li

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  14. The role of AURKA/miR-199b-3p in hepatocellular carcinoma cells.Journal of clinical laboratory analysis · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hui ZhangDepartment of Radiology, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, China.
Junhui BaoDepartment of Radiology, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, China.
Shahe ZhaoDepartment of Radiology, the First Hospital of Yongnian District, Handan, Hebei, China.
Zhongchao HuoDepartment of Radiotherapy, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, China.
Baowei LiDepartment of Radiology, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, China.
Hebei University of Engineering · CNAffiliated Hospital of Hebei University · CNHospital of Hebei Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatocellular carcinoma (HCC) is the most common and prevalent cancer type among liver cancers. In this study, expression of miR-490-3p and aurora kinase A gene ( MATERIAL AND

methodsThe dual luciferase reporter assay serves to verify the target relationship between miR-490-3p and

resultsThe experiment results showed that miR-490-3p expression was down-regulated and

conclusionsmiR-490-3p could down-regulate the expression of

Indexed as

AURKAhepatocellular carcinomamigrationmiR-490-3pproliferation

Identifiers

PMID32190151
PMCPMC7069437
OpenAlexW2998874790

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.