Evidence map›Paper›PMID 32190140›Full record

ArticleArchives of medical science : AMS2020

Frequency of thyroid nodules and thyroid cancer in thyroidectomized patients with Graves' disease.

Caglar Keskin, Mustafa Sahin, Rovshan Hasanov, Berna Imge Aydogan, Ozgur Demir, Rıfat Emral, Sevim Gullu, Murat Faik Erdogan, Vedia Gedik, Ali Riza Uysal and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of medical science : AMS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Caglar KeskinDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Mustafa SahinDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Rovshan HasanovDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Berna Imge AydoganDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Ozgur DemirDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Rıfat EmralDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Sevim GulluDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Murat Faik ErdoganDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Vedia GedikDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Ali Riza UysalDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Nilgun BaskalDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Demet CorapciogluDepartment of Endocrinology and Metabolic Disease, School of Medicine, Ankara University, Ankara, Turkey.
Ankara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIncidental thyroid cancers are frequently detected in patients operated on for Graves' disease (GD). There are no clear data about the incidence and risk factors of incidental thyroid cancer in operated GD patients. The aim of this study is to evaluate the risk of thyroid carcinoma in surgically treated GD patients. MATERIAL AND

methodsThe data of 121 GD patients who underwent total thyroidectomy in a single center between 2005 and 2015 were retrospectively evaluated. The diagnosis of thyroid cancer was based on pathological examination.

resultsThyroid cancer was demonstrated in postoperative pathology specimens of 34 patients who were surgically treated for GD (28.1%). Preoperative thyroid ultrasonography (USG) revealed a nodular goiter in 62 (51.2%) patients. Nodules were not detected in the other 59 (48.8%) patients with GD. The frequency of thyroid cancer was significantly higher in patients with nodules (38% vs. 16%;

conclusionsThe incidence of thyroid cancer was higher in patients who underwent surgery for GD. In addition to a careful physical examination in the follow-up of the patients with GD, ultrasonographic evaluation should be performed. Surgical treatment should not be delayed in patients with GD when indicated.

Indexed as

Graves’ diseasethyroid cancerthyroid nodule

Identifiers

PMID32190140
PMCPMC7069426
OpenAlexW2909769521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.