ReviewJournal of contemporary brachytherapy2020
The role of brachytherapy in the management of brain metastases: a systematic review.
Review in Journal of contemporary brachytherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Symptomatic radiation necrosis following intracranial brachytherapy: a systematic review and meta-analysis.Journal of neuro-oncology · 2026Pooled it
- Intra-cavitary radiotherapy for surgically resected brain metastases: a comprehensive analysis including an individual patient data meta-analysis of intraoperative radiotherapy (IORT) and brachytherapy (IBT).Journal of neuro-oncology · 2025Pooled it
- Brain metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions.Neuro-oncology · 2022Guideline
- Long-term treatment of metastatic adenoid cystic carcinoma with sequential brachytherapy and stereotactic body radiotherapy.Radiation oncology journal · 2024Article
- Brachytherapy in Brain Metastasis Treatment: A Scoping Review of Advances in Techniques and Clinical Outcomes.Cancers · 2024Article
- Rate of pachymeningeal failure following adjuvant WBRT vs SRS in patients with brain metastases.Clinical and translational radiation oncology · 2024Article
- Editorial: Radiotherapy strategies for precise treatment on brain metastases.Frontiers in oncology · 2024Article
- An Overview of Systemic Targeted Therapy in Renal Cell Carcinoma, with a Focus on Metastatic Renal Cell Carcinoma and Brain Metastases.Current issues in molecular biology · 2023Review
- A Neurosurgical Perspective on Brain Metastases from Renal Cell Carcinoma: Multi-Institutional, Retrospective Analysis.Biomedicines · 2023Article
- Three-dimensional template combined with MR-guided iodine-125 brachytherapy for recurrent brain metastases.Journal of contemporary brachytherapy · 2023Article
- Dosimetric Impact of Source Displacement in GammaTile Surgically Targeted Radiation Therapy for Gliomas.Cureus · 2023Article
- Patient-specific radiological protection precautions following Cs collagen embedded Cs-131 implantation in the brain.Journal of applied clinical medical physics · 2022Article
- Update on the Management of Brain Metastasis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- Salvage resection plus cesium-131 brachytherapy durably controls post-SRS recurrent brain metastases.Journal of neuro-oncology · 2022Article
- The role of cesium-131 brachytherapy in brain tumors: a scoping review of the literature and ongoing clinical trials.Journal of neuro-oncology · 2022Article
- CT-MR Image Fusion for Post-Implant Dosimetry Analysis in Brain Tumor Seed Implantation- a Preliminary Study.Disease markers · 2022Article
- Diffusing alpha-emitters radiation therapy in combination with temozolomide or bevacizumab in human glioblastoma multiforme xenografts.Frontiers in oncology · 2022Article
- Review of Current Principles of the Diagnosis and Management of Brain Metastases.Frontiers in oncology · 2022Review
- Surgical advances in the management of brain metastases.Neuro-oncology advances · 2021Article
- In regard to Minniti et al.: Current status and recent advances in resection cavity irradiation of brain metastases-roundup to cover all angles.Radiation oncology (London, England) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBrain metastases have a highly variable prognosis depending on the primary tumor and associated prognostic factors. Standard of care for patients with these tumors includes craniotomy, stereotactic radiosurgery (SRS), or whole brain radiotherapy (WBRT) for patients with brain metastases. Brachytherapy shows great promise as a therapy for brain metastases, but its role has not been sufficiently explored in the current literature. MATERIAL AND
methodsThe PubMed, Cochrane, and Scopus databases were searched using a combination of search terms and synonyms for brachytherapy, brain neoplasms, and brain metastases, for articles published between January 1
resultsMost data focused on
conclusionsFor a variety of reasons including absence of physician expertise in brachytherapy, lack of published data on treatment outcomes, and rates of radiation necrosis, brachytherapy is not presently a part of standard paradigm for brain metastases. However, our review indicates brachytherapy as a modality that offers excellent local control and quality of life, and suggested that its use should be further studied.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.