Evidence map›Paper›PMID 32189986›Full record

ArticleInterdisciplinary toxicology2019

Short communication: Chlorpromazine causes a time-dependent decrease of lipids in

Dina Muhieddine, Mohamad Moughnié, Ziad Abdel-Razzak

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interdisciplinary toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dina MuhieddineLaboratory of Experimental and Clinical Pharmacology, Faculty of Sciences, Rafic Hariri Campus, Lebanese University, Beirut, Lebanon.
Mohamad MoughniéLaboratory of Experimental and Clinical Pharmacology, Faculty of Sciences, Rafic Hariri Campus, Lebanese University, Beirut, Lebanon.
Ziad Abdel-RazzakLaboratory of Experimental and Clinical Pharmacology, Faculty of Sciences, Rafic Hariri Campus, Lebanese University, Beirut, Lebanon.
Lebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlorpromazine (CPZ) is still a commonly prescribed antipsychotic which causes poorly understood idiosyncratic toxicity such as cholestasis, phospholipidosis and steatosis. CPZ has diverse cellular targets and exerts various toxicity mechanisms whose exploration is necessary to understand CPZ side effects. We report here that CPZ causes a decrease of total lipid content in

Indexed as

chlorpromazine toxicitylipidsoxidative stressphenothiazineSaccharomyces cerevisiae

Identifiers

PMID32189986
PMCPMC7061449
OpenAlexW3008728917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.