ReviewInterdisciplinary toxicology2019
The pathway of lead through the mother's body to the child.
Review in Interdisciplinary toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Systematic Review on Neurotoxic Implications of Lead-Induced Gene Expression Alterations in the Etiology of Alzheimer's Disease.Cellular and molecular neurobiology · 2025Pooled it
- Lead and arsenic intoxications by traditional and alternative medicine: men are more sensitive than women.Naunyn-Schmiedeberg's archives of pharmacology · 2025Pooled it
- Incidental Changes in Urinary Lead Excretion Following Intra-Venous Ca-DTPA Administration in Patients Treated Primarily for Gadolinium Exposure.Journal of xenobiotics · 2026Article
- Maternal blood lead levels and proximity to legacy mining contamination in Kabwe, Zambia: socioeconomic disparities and potential implications on fetal health.Environmental science and pollution research international · 2026Article
- Oxidative Stress-Related Metabolomic Alterations in Pregnancy: Evidence from Exposure to Air Pollution, Metals/Metalloid, and Tobacco Smoke.Antioxidants (Basel, Switzerland) · 2025Review
- Dentin Metal and Trace Elements in Deciduous Teeth: Findings from Project Viva.Environmental science & technology · 2025Article
- Africa, an Emerging Exporter of Turmeric: Combating Fraud with Rapid Detection Systems.Foods (Basel, Switzerland) · 2025Review
- Testicular Histological Changes and Ki-67 Expression in Lead (II) Oxide Toxicity among Neonatal Wistar Rats and Modulatory Role of Retinol.Archives of Razi Institute · 2025Article
- Prevalence of Exposure to Environmental Metal Mixtures Among Pregnant Women in the United States National Health and Nutrition Examination Survey (NHANES) 1999-2018.Journal of xenobiotics · 2025Article
- Association between maternal blood lead levels and prevalence of dental caries in the primary dentition of children.Environmental health and preventive medicine · 2025Article
- Sex dependent intergenerational effects of lead in mouse model.Scientific reports · 2024Article
- Interplay Between Vitamin D Levels and Heavy Metals Exposure in Pregnancy and Childbirth: A Systematic Review.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024Review
- Metal Levels in Striped Dolphins (Animals : an open access journal from MDPI · 2024Article
- Trace metals concentrations in fresh milk from dairy farms and stores: An assessment of human health risk.Toxicology reports · 2024Article
- Isotopic analysis of formula milk reveals potential challenges in geolocating bottle-fed babies.Scientific reports · 2024Article
- Blood lead levels in pregnant women and their newborn infants at an Indian teaching hospital.Journal of family medicine and primary care · 2024Article
- Relationship between lead concentration in maternal and umbilical cord blood and some neonatal outcomes in primiparous opium-dependent mothers in Zahedan, Southeast of Iran in 2022.BMC pregnancy and childbirth · 2023Article
- Correlations Among Maternal and Infant Factors, Lead Exposure, and Serum Prolactin Levels During Lactation: A Cross-sectional Study in Indonesia.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023Article
- Radon and Neoplasms.Toxics · 2023Article
- The Role of Protein Intake on the Total Milk Protein in Lead-Exposed Lactating Mothers.Nutrients · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Placenta, the organ on which great attention is concentrated during pregnancy, represents an ineffective barrier to the transfer of hazardous heavy metals, mainly lead, into the foetus. The presence of lead in the placenta is an environmental hazard for a person's future. Due to hormonal changes, lead is released during pregnancy into the bloodstream of the mother from deposits in the bones and in the teeth, where it has accumulated for years as a result of a contaminated environment. Since lead is a neurotoxic metal, exposure to lead during prenatal and postnatal development can cause serious neurocognitive damage and hence the development of an Attention Deficit Hyperactivity Disorder (ADHD) in a developing human. Our work provides an overall picture of the "toxic pathway" of lead through the mother's body, the risks arising from its transplacental transfer and its accumulation in the developing foetus as well as effective prevention to protect all newborns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.