Evidence map›Paper›PMID 32189351›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2021

Association of Body Composition, Physical Functioning, and Protein Intake in Adult Patients With Mitochondrial Diseases.

Heidi E E Zweers, Valentine Bordier, Jeanne In 't Hulst, Mirian C H Janssen, Geert J A Wanten, Susanne Leij-Halfwerk

Open access · hybridAbstract read
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Optimized Nutrition in Mitochondrial Disease Correlates to Improved Muscle Fatigue, Strength, and Quality of Life.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Heidi E E ZweersDepartment of Gastroenterology and Hepatology-Dietetics, Radboudumc, Nijmegen, the Netherlands.ORCID 0000-0003-3465-4646
Valentine BordierDepartment of Nutrition and dietetics, HAN University of Applied Sciences, Nijmegen, the Netherlands.
Jeanne In 't HulstDepartment of Gastroenterology and Hepatology-Dietetics, Radboudumc, Nijmegen, the Netherlands.
Mirian C H JanssenDepartment of Internal Medicine, Radboudumc, Nijmegen, the Netherlands.
Geert J A WantenDepartment of Gastroenterology and Hepatology, Radboudumc, Nijmegen, the Netherlands.
Susanne Leij-HalfwerkDepartment of Gastroenterology and Hepatology-Dietetics, Radboudumc, Nijmegen, the Netherlands.
HAN University of Applied Sciences · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether decreased physical functioning of patients with mitochondrial disease (MD) is related to altered body composition or low protein intake needs clarification at the background of the nutrition state.

methodsIn this 2-site cross-sectional study, MD patients were age-, body mass index (BMI)-, and gender-matched to controls. Body composition was assessed by dual-energy x-ray absorptiometry. Physical functioning was measured by handgrip strength, 6-minute walking test, 30-second sit-to-stand test (30SCT), and 6-minute mastication test. Total daily protein intake was calculated by 3-day food records. Malnutrition was assessed by Patient-Generated Subjective Global Assessment and the Global Leadership Initiative on Malnutrition (GLIM) criteria and sarcopenia by the 2018 consensus. Data were analyzed using independent samples t-tests, Fisher exact test, and Spearman and Pearson correlation coefficients.

resultsThirty-seven MD patients (42 ± 12 years, BMI: 23 ± 4 kg/m

conclusionsMuscle strength is related to body composition and protein intake in MD patients. This, in combination with the high incidence of both malnutrition and sarcopenia, warrants individual nutrition assessment in MD patients.

Indexed as

Mitochondrial DiseasesSarcopeniaAbsorptiometry, PhotonAdultBody CompositionBody Mass IndexCross-Sectional StudiesFemaleHand StrengthHumansMaleBIAbody compositionDXAhandgrip strengthmalnutritionmitochondrial diseasenutrition assessmentphysical functioningsarcopenia

Identifiers

PMID32189351
PMCPMC7891597
OpenAlexW3012457172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.