Evidence map›Paper›PMID 32189159›Full record

ReviewHead and neck pathology2021

Tonsillar p16-Positive Follicular Dendritic Cell Sarcoma Mimicking HPV-Related Oropharyngeal Squamous Cell Carcinoma: A Case Report and Review of Reported Cases.

Bailey Hutchison, Sam Sadigh, Judith A Ferry, Trisha M Shattuck, William C Faquin

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in Head and neck pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. A Rare Case of Follicular Dendritic Cell Sarcoma of Tonsil-Clinical Report.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  2. Article
  3. Article
  4. Follicular dendritic cell sarcoma of the tonsil: case report and review of literature.International journal of clinical and experimental pathology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Bailey HutchisonDepartment of Pathology, Massachusetts General Hospital, Boston, MA, USA. bhutchison@partners.org.
Sam SadighDepartment of Pathology, Massachusetts General Hospital, Boston, MA, USA.
Judith A FerryDepartment of Pathology, Massachusetts General Hospital, Boston, MA, USA.
Trisha M ShattuckCarolinas Pathology, Atrium Health Carolinas Medical Center, Charlotte, NC, USA.
William C FaquinDepartment of Pathology, Massachusetts General Hospital, Boston, MA, USA.
Massachusetts General Hospital · USCarolinas Medical Center · USMassachusetts Eye and Ear Infirmary · US

Funding

Strategies to Overcome Immune Resistance in Head and Neck CancersP01CA240239 · NCI · YALE UNIVERSITY · PI MEMPEL, THORSTEN ROMAN · 2019 to 2023
$8.4M
NCI NIH HHS P01 CA240239
6 · The paper itself

Abstract

Follicular dendritic cell sarcoma (FDCS) is a rare entity which can share morphologic features with non-keratinizing squamous cell carcinoma. Recent reports suggest that up to half of FDCSs show immunohistochemical positivity for p16 (Zhang et al., in Hum Pathol 66:40-47, 2017), a stain that is conventionally used in the risk stratification of oropharyngeal squamous cell carcinoma (OPSCC). Herein, we report a case of p16-positive FDCS with clinical and histomorphologic overlap with human papilloma virus (HPV)-related OPSCC.

Indexed as

AdultBiomarkers, TumorCyclin-Dependent Kinase Inhibitor p16Dendritic Cell Sarcoma, FollicularDiagnosis, DifferentialHumansMaleOropharyngeal NeoplasmsSquamous Cell Carcinoma of Head and NeckTonsillar NeoplasmsBiomarkers, TumorCDKN2A protein, humanCyclin-Dependent Kinase Inhibitor p16

Identifiers

PMID32189159
PMCPMC8010052
OpenAlexW3012533339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.