Evidence map›Paper›PMID 32189004›Full record

ArticleActa dermato-venereologica2020

Increasing Costs of Skin Cancer due to Increasing Incidence and Introduction of Pharmaceuticals, 2007-2017.

Eline Noels, Loes Hollestein, Kees Luijkx, Marieke Louwman, Carin de Uyl-de Groot, Renate van den Bos, Astrid van der Veldt, Dirk Grünhagen, Marlies Wakkee

Abstract readComparative Study
In one paragraph

Article in Acta dermato-venereologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Impact of skin biopsy practices: A comprehensive nationwide study on skin cancer and melanoma biopsies.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Article
  4. Non-invasive infrared thermography for screening, diagnosis and monitoring of skin cancer.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. The effects of exposure to solar radiation on human health.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Diagnostics (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, Update 2020.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eline NoelsDepartment of Dermatology , Erasmus Medical Center Cancer Institute, Dr. Molewaterplein 40, NL-3015 GD Rotterdam, The Netherlands. E-mail: m.wakkee@erasmusmc.nl.
Loes Hollestein
Kees Luijkx
Marieke Louwman
Carin de Uyl-de Groot
Renate van den Bos
Astrid van der Veldt
Dirk Grünhagen
Marlies Wakkee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin cancer is the most common type of cancer and its incidence is increasing. The objective of this study was to describe the trends in reimbursed drug and hospital costs of benign and (pre)malignant skin tumours, and to present future projections. Therefore, nationwide hospital and drug reimbursement data (for the period 2007-17) were used. In 2017, malignant skin tumours were the 4th most costly cancer in the Netherlands (after breast, colorectal, and lung cancer). The total costs for skin tumours increased from €278 million for 384,390 patients (in 2007) to €465 million for 578,355 patients (in 2017). Drug costs increased from €0.7 million to €121 million (over the period 2007-17), resulting in a 26% share of overall costs in 2017. Future costs are projected to reach €1.35 billion in 2030. In conclusion, the increasing costs of skin cancer are strongly affected by the increasing incidence and introduction of expensive drugs, and future projections are for an alarming increase.

Indexed as

Antineoplastic AgentsDatabases, FactualDrug CostsForecastingHospital CostsHumansIncidenceInsurance, Health, ReimbursementModels, EconomicNetherlandsSkin NeoplasmsTime FactorsAntineoplastic Agentshealthcare costshealth expenditureskin cancer: skin neoplasm

Identifiers

PMID32189004
PMCPMC9137355

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.