ArticleCommunications biology2020
Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice.
Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- The macrophage entry mechanism of SARS-CoV-2 mediated by surface CD98/TMPRSS11E complex is associated with the cellular tropism toward proinflammatory M1 and pathogenesis.Respiratory research · 2026Article
- The role of metabolic crosstalk between Intestinal epithelial cells and immune cells in inflammatory bowel disease and targeting strategies.Frontiers in immunology · 2026Review
- Engineered Metal-Organic Frameworks for Targeted CRISPR/Cas9 Gene Editing.ACS pharmacology & translational science · 2025Review
- Transfer of cardiomyocyte-derived extracellular vesicles to neighboring cardiac cells requires tunneling nanotubes during heart development.Theranostics · 2024Article
- Crosstalk between gut microbiota and gut resident macrophages in inflammatory bowel disease.Journal of translational internal medicine · 2023Article
- Macrophages in intestinal homeostasis and inflammatory bowel disease.Nature reviews. Gastroenterology & hepatology · 2023Review
- Diesel Exhaust Particle (DEP)-induced glucose intolerance is driven by an intestinal innate immune response and NLRP3 activation in mice.Particle and fibre toxicology · 2023Article
- Single cell RNA-sequencing profiling to improve the translation between human IBD andFrontiers in immunology · 2023Review
- Macrophage metabolism in the intestine is compartment specific and regulated by the microbiota.Immunology · 2022Article
- Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity.Communications biology · 2022Article
- Analyzing high-dimensional cytometry data using FlowSOM.Nature protocols · 2021Review
- Host-microbe cross-talk governs amino acid chirality to regulate survival and differentiation of B cells.Science advances · 2021Article
- Amino Acid Transport and Metabolism in Myeloid Function.Frontiers in immunology · 2021Review
- Obesity in Humans Is Characterized by Gut Inflammation as Shown by Pro-Inflammatory Intestinal Macrophage Accumulation.Frontiers in immunology · 2021Observational
- BCAT1 affects mitochondrial metabolism independently of leucine transamination in activated human macrophages.Journal of cell science · 2020Article
- Connecting the Dots Between Inflammatory Bowel Disease and Metabolic Syndrome: A Focus on Gut-Derived Metabolites.Nutrients · 2020Review
- Establishment of bone marrow-derived M-CSF receptor-dependent self-renewing macrophages.Cell death discovery · 2020Article
Corrections and comments
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Authors and funding
11 authors at 20 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comprehensive development is critical for gut macrophages being essential for the intestinal immune system. However, the underlying mechanisms of macrophage development in the colon remain elusive. To investigate the function of branched-chain amino acids in the development of gut macrophages, an inducible knock-out mouse model for the branched-chain amino acid transporter CD98hc in CX3CR1
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.