Evidence map›Paper›PMID 32188884›Full record

ArticleScientific reports2020

Prevalence of HPV infection among sexually active adolescents and young adults in Brazil: The POP-Brazil Study.

Eliana Marcia Wendland, Luisa Lina Villa, Elizabeth R Unger, Carla Magda Domingues, Adele Schwartz Benzaken, POP-Brazil Study Group

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 7 institutions in 2 countries.

Eliana Marcia WendlandHospital Moinhos de Vento, Porto Alegre, Brazil. elianawend@gmail.com.
Luisa Lina VillaUniversidade de São Paulo and Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, Brazil.ORCID http://orcid.org/0000-0003-4074-2335
Elizabeth R UngerDivision of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Diseases, Centers for Disease Control and Prevention, Atlanta, USA.ORCID http://orcid.org/0000-0002-2925-5635
Carla Magda DominguesNational Immunization Program, Ministry of Health, Brasilia, Brazil.
Adele Schwartz BenzakenTropical Medicine Foundation Heitor Vieira Dourado and Global Aids Healthcare Foundation, Manaus, Brazil.
POP-Brazil Study Group
Universidade Federal do Rio Grande do Sul · BRHospital Moinhos de Vento · BRMinistério da Saúde · BRUniversidade de São Paulo · BRCenters for Disease Control and Prevention · USFundação de Medicina Tropical · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For Brazil, there are no nationwide data on HPV prevalence against which the impact of the HPV immunization program can be measured in the future. Therefore, we aim to evaluate the prevalence of genital HPV infection among adolescents and young adults in Brazil. A cross-sectional, multicentric, nationwide survey was conducted between September 2016 and November 2017. Sexually active unvaccinated women and men aged 16 to 25 years old were recruited from 119 public primary care units, including all 26 state capitals and the Federal District. All participants answered a face-to-face interview and provided biological samples for genital HPV analysis. We used an automated DNA extraction method and HPV genotyping was performed using the Linear Array genotyping test (Roche). Of 7,694 participants, 53.6% (95% CI 51.4-55.8) were positive for any HPV type. The prevalence of high-risk HPV types was significantly higher in women (38.6% vs. 29.2%, P < 0·001). The HPV types included in the quadrivalent vaccine were detected in 1002 (14.8%) specimens, with a different pattern of HPV infection between sexes. Characteristics associated with overall HPV detection included female gender, self-declaration of race as brown/pardo, lower socioeconomic class, single or dating, current smoking and having 2 or more sex partners in the past year. We found a high prevalence of HPV, with significant differences between regions. Our data provide information that may be considered when developing HPV prevention policies and constitute a baseline against which the impact of the HPV immunization program in Brazil can be measured in future years.

Indexed as

AdolescentAdultBrazilCross-Sectional StudiesFemaleGenotypeHumansMaleMass ScreeningPapillomaviridaePapillomavirus InfectionsPrevalencePublic Health SurveillanceSexually Transmitted Diseases, ViralYoung Adult

Identifiers

PMID32188884
PMCPMC7080737
OpenAlexW3011030403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.