Evidence map›Paper›PMID 32188805›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Influenza Vaccination-associated Acute Thrombocytopenia and Diffuse Alveolar Hemorrhage.

Yuji Yamamoto, Yuko Ohara, Ami Iwai, Reina Hara, Takanori Matsuki, Kiyoharu Fukushima, Yohei Oshitani, Hiroyuki Kagawa, Kazuyuki Tsujino, Kenji Yoshimura and 4 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Yuji YamamotoDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Yuko OharaDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Ami IwaiDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Reina HaraDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Takanori MatsukiDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Kiyoharu FukushimaDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Yohei OshitaniDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Hiroyuki KagawaDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Kazuyuki TsujinoDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Kenji YoshimuraDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Mari MikiDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Keisuke MikiDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Masahide MoriDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
Hiroshi KidaDepartment of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Japan.
National Hospital Organization · JPToneyama National Hospital · JPYodogawa Christian Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza vaccination can trigger various adverse reactions, and thrombocytopenia is also rarely reported. Although patients with mild thrombocytopenia are sometimes asymptomatic, severe thrombocytopenia can cause severe bleeding. We herein report a rare case of severe thrombocytopenia that occurred within one day of influenza vaccination and diffuse alveolar hemorrhage (DAH) leading to acute respiratory failure. The patient was treated with glucocorticoid pulse therapy, intravenous immunoglobulin, and temporary mechanical ventilation, and eventually he made a full recovery. Vaccine-related thrombocytopenia and DAH should be considered adverse reactions, even if they develop very soon after vaccination.

Indexed as

AgedHemorrhageHumansInfluenza VaccinesLung DiseasesMaleRespiration, ArtificialRespiratory Distress SyndromeSeverity of Illness IndexThrombocytopeniaInfluenza Vaccinesacute respiratory failureadverse reactionvaccine

Identifiers

PMID32188805
PMCPMC7402960
OpenAlexW3011912135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.