Evidence map›Paper›PMID 32188783›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.

Hyun-Seo Kang, Carolina Sánchez-Rico, Stefanie Ebersberger, F X Reymond Sutandy, Anke Busch, Thomas Welte, Ralf Stehle, Clara Hipp, Laura Schulz, Andreas Buchbender and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  14. Connecting sequence features within the disordered C-terminal linker ofProceedings of the National Academy of Sciences of the United States of America · 2022
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  15. Review
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  17. The Charged Linker Modulates the Conformations and Molecular Interactions of Hsp90.Chembiochem : a European journal of chemical biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Hyun-Seo KangInstitute of Structural Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany.ORCID 0000-0003-4029-5096
Carolina Sánchez-RicoInstitute of Structural Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Stefanie EbersbergerInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.ORCID 0000-0001-8493-8239
F X Reymond SutandyInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Anke BuschInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Thomas WelteDynamic Biosensors, 82152 Martinsried, Germany.ORCID 0000-0003-4396-7249
Ralf StehleChemistry Department, Biomolecular NMR and Center for Integrated Protein Science Munich, Technical University of Munich, 85748 Garching, Germany.
Clara HippChemistry Department, Biomolecular NMR and Center for Integrated Protein Science Munich, Technical University of Munich, 85748 Garching, Germany.
Laura SchulzInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Andreas BuchbenderInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.ORCID 0000-0001-5808-2748
Kathi ZarnackBuchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.ORCID 0000-0003-3527-3378
Julian KönigInstitute of Molecular Biology (IMB), 55128 Mainz, Germany; j.koenig@imb-mainz.de sattler@helmholtz-muenchen.de.ORCID 0000-0002-9398-5421
Michael SattlerInstitute of Structural Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany; j.koenig@imb-mainz.de sattler@helmholtz-muenchen.de.ORCID 0000-0002-1594-0527
Institute of Molecular Biology · DECenter for Integrated Protein Science Munich · DEDynamic Biosensors (Germany) · DEGoethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recognition of

Indexed as

AnimalsCattleChromatin ImmunoprecipitationHumansMagnetic Resonance SpectroscopyMiceRibonucleoside Diphosphate ReductaseRNARNA Recognition MotifSplicing Factor U2AFRibonucleoside Diphosphate Reductaseribonucleotide reductase M2RNASplicing Factor U2AFU2AF2 protein, humaniCLIPprotein–RNA interactionssplicingstructural biologyU2 auxiliary factor

Identifiers

PMID32188783
PMCPMC7132250
OpenAlexW3012299396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.