Evidence map›Paper›PMID 32188609›Full record

ReviewBMJ case reports2020

Subtle neuropsychiatric symptoms of glioblastoma multiforme misdiagnosed as depression.

Raphael Jerome Leo, Jill N Frodey, Matthew L Ruggieri

Abstract readCase ReportsReview
In one paragraph

Review in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Conducting a randomized controlled clinical trial on palliative care in patients with glioblastoma - what are the challenges?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Left frontal lobe glioblastoma multiforme masquerading as psychosis: A case report.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raphael Jerome LeoDepartment of Psychiatry, SUNY at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA rleo@buffalo.edu.
Jill N FrodeyDepartment of Psychiatry, SUNY at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Matthew L RuggieriDepartment of Psychiatry, SUNY at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma multiforme (GBM) is the most common of the aggressive primary brain tumours arising in adults and has a dire prognosis. Neuropsychiatric symptoms can vary significantly among afflicted persons; psychiatric disturbances may be the predominant presenting symptoms. Distinguishing between functional psychiatric disorders, particularly depression, from other subtle neuropsychiatric disturbances that may accompany GBM can be challenging. The authors present a clinical case and review of the literature in an attempt to highlight the special considerations that should be taken into account when evaluating patients who present with late-onset or atypical symptoms, refractory psychiatric symptoms, or subtle neurological disturbances signalling the need for diagnostic assessment, particularly neuroimaging, for the presence of a tumour. Early diagnosis is critical for improvement in quality of life.

Indexed as

Brain NeoplasmsDepressive DisorderDiagnosis, DifferentialGlioblastomaHumansMagnetic Resonance ImagingMaleMiddle AgedNeurocognitive DisordersCentral Nervous System cancerpsychiatry

Identifiers

PMID32188609
PMCPMC7078688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.