Evidence map›Paper›PMID 32188533›Full record

ArticleInternational psychogeriatrics2021

The roles of study setting, response bias, and personality in subjective memory complaints of cognitively normal older adults.

Sarah M Goldberg, Oscar L Lopez, Ann D Cohen, William E Klunk, Howard A Aizenstein, Akiko Mizuno, Beth E Snitz

Open access · diamondAbstract read
In one paragraph

Article in International psychogeriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sarah M GoldbergDepartment of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0001-7308-1516
Oscar L LopezDepartment of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Ann D CohenDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
William E KlunkDepartment of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Howard A AizensteinDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Akiko MizunoDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Beth E SnitzDepartment of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
University of Pittsburgh · US

Funding

TREATMENT OF DEPRESSION IN ALZHEIMER'S DISEASEP50AG005133 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOPEZ, OSCAR L. · 1985 to 2019
$43.0M
Roles of Gray Matter Brain Aging and Small Vessel Disease in AD PathophysiologyRF1AG025516 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AIZENSTEIN, HOWARD J, VILLEMAGNE, VICTOR LUIS · 2014 to 2021
$9.0M
Roles of Gray Matter Brain Aging and Small Vessel Disease in AD PathophysiologyR01AG025516 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Victor Luis Villemagne · 2024 to 2026
$4.4M
AMYLOID PATHOLOGY AND COGNITION IN NORMAL ELDERLYR37AG025516 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLUNK, WILLIAM E · 2005 to 2014
$4.3M
Subjective Cognitive Complants, Cognitive Decline and B-Amyloid Deposition in NonK23AG038479 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SNITZ, BETH · 2010 to 2014
$577k
NIA NIH HHS K23 AG038479NIA NIH HHS P50 AG005133NIA NIH HHS R01 AG025516NIA NIH HHS R37 AG025516NIA NIH HHS RF1 AG025516
6 · The paper itself

Abstract

objectivesThis study investigated subjective memory complaints in older adults and the roles of setting, response bias, and personality.

designCognitively normal older adults from two settings completed questionnaires measuring memory complaints, response bias, and personality. SETTINGS: (A) Neuroimaging study with community-based recruitment and (B) academic memory clinic.

participantsCognitively normal older adults who (A) volunteer for research (N = 92) or (B) self-referred to a memory clinic (N = 20). MEASUREMENTS: Neuropsychological evaluation and adjudication of normal cognitive status were done by the neuroimaging study or memory clinic. This study administered self-reports of subjective memory complaints, response bias, five-factor personality, and depressive symptoms. Primary group differences were examined with secondary sensitivity analyses to control for sex, age, and education differences.

resultsThere was no significant difference in over-reporting response bias between study settings. Under-reporting response bias was higher in volunteers. Cognitive complaints were associated with response bias for two cognitive complaint measures. Neuroticism was positively associated with over-reporting in evaluation-seekers and negatively associated with under-reporting in volunteers. The relationship was reversed for Extraversion. Under-reporting bias was positively correlated with Agreeableness and Conscientiousness in volunteers.

conclusionEvaluation-seekers do not show bias toward over-reporting symptoms compared to volunteers. Under-reporting response bias may be important to consider when screening for memory impairment in non-help-seeking settings. The Memory Functioning Questionnaire was less sensitive to reporting biases. Over-reporting may be a facet of higher Neuroticism. Findings help elucidate psychological influences on self-perceived cognitive decline and help seeking in aging and may inform different strategies for assessment by setting.

Indexed as

CognitionDiagnostic Self EvaluationHealth SurveysMemoryPersonalitySelf ReportAgedAgingBiasCognitive AgingFemaleHealthy VolunteersHumansMaleMemory DisordersNeuropsychological Testsagingcognitive assessmentmemorypsychogeriatricsrisk factors

Identifiers

PMID32188533
PMCPMC7501183
OpenAlexW3011031726

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.