Evidence map›Paper›PMID 32188461›Full record

ArticleHealth and quality of life outcomes2020

Validation of the SF12 mental and physical health measure for the population from a low-income country in sub-Saharan Africa.

Julius Ohrnberger, Laura Anselmi, Eleonora Fichera, Matt Sutton

Abstract readValidation Study
In one paragraph

Article in Health and quality of life outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. A cross-sectional observational study of quality of life in adult short bowel syndrome patients: What role does autologous gut reconstruction play?Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julius OhrnbergerSchool of Public Health, MRC Centre for Global Infectious Disease Analysis, Imperial College London, London, England. j.ohrnberger@imperial.ac.uk.
Laura AnselmiDivision of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, England.
Eleonora FicheraDepartment of Economics, University of Bath, Manchester, England.
Matt SuttonDivision of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, England.

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
STATISTICAL DATA ENCLAVE COREP30AG012836 · NIA · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, HANS-PETER · 1999 to 2024
$14.0M
Population Science Research Center Development CoreR24HD044964 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI SMITH, HERBERT L. · 2003 to 2017
$9.8M
Consequences of High Morbidity and Mortality in a Low-Income CountryR01HD053781 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, HANS-PETER · 2007 to 2011
$2.9M
AIDS/HIV RISK, Marriage and Sexual Relations in MalawiR01HD044228 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, HANS-PETER · 2003 to 2006
$1.6M
Imaging and therapy of intrauterine inflammation induced perinatal brain injuryK08HD050652 · NICHD · WAYNE STATE UNIVERSITY · PI KANNAN, SUJATHA · 2007 to 2010
$510k
Subjective Expectations and Health-Related Behavior R03HD058976 · NICHD · RAND CORPORATION · PI DELAVANDE, ADELINE · 2009 to 2010
$190k
Medical Research Council MR/R015600/1NIAID NIH HHS P30 AI045008NIA NIH HHS P30 AG012836NICHD NIH HHS K08 HD050652NICHD NIH HHS R01 HD044228NICHD NIH HHS R01 HD053781NICHD NIH HHS R03 HD058976NICHD NIH HHS R24 HD044964The University of Manchester President's Doctoral Scholarship
6 · The paper itself

Abstract

introductionThe Short Form Survey 12-item (SF12) mental and physical health version has been applied in several studies on populations from Sub-Saharan Africa. However, the SF12 has not been computed and validated for these populations. We address in this paper these gaps in the literature and use a health intervention example in Malawi to show the importance of our analysis for health policy.

methodsWe firstly compute the weights of the SF12 physical and mental health measure for the Malawian population using principal component analysis on a sample of 2838 adults from wave four (2006) of Malawian Longitudinal Study of Aging (MLSFH). We secondly test the construct validity of our computed and the US-population weighted SF12 measures using regression analysis and Fixed Effect estimation on waves four, seven (2012) and eight (2013) of the MLSFH. Finally, we use a Malawian cash transfer programme to exemplify the implications of using US- and Malawi-weighted SF12 mental health measures in policy evaluation.

resultsWe find that the Malawian SF12 health measure weighted by our computed Malawian population weights is strongly associated with other mental health measures (Depression:-0.501, p = < 0.001; Anxiety:-1.755; p = < 0.001) and shows better construct validity in comparison to the US-weighted SF12 mental health component (rs = 0.675 versus rs = 0.495). None of the SF12 measures shows strong associations with other measures of physical health. The estimated average effect of the cash transfer is significant when using the Malawi-weighted SF12 mental health measure (treatment effect: 1.124; p = < 0.1), but not when using the US-weighted counterpart (treatment effect: 1.129; p > 0.1). The weightings affect the size of the impacts across mental health quantiles suggesting that the weighting scheme matters for empirical health policy analysis.

conclusionMental health shows more pronounced associations with the physical health dimension in a Low-Income Country like Malawi compared to the US. This is important for the construct validity of the SF12 health measures and has strong implications in health policy analysis. Further analysis is required for the physical health dimension of the SF12.

Indexed as

AdolescentAdultFemaleHealth StatusHumansLongitudinal StudiesMalawiMaleMental HealthPovertyQuality of LifeRegression AnalysisSurveys and QuestionnairesHealth policyLMICsMalawiMental healthPhysical healthSF12 scale validation

Identifiers

PMID32188461
PMCPMC7081543

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.