ArticleBMC plant biology2020
An exclusion mechanism is epistatic to an internal detoxification mechanism in aluminum resistance in Arabidopsis.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- TIP3;2 is a tonoplast transporter contributed to nickel detoxification in Arabidopsis thaliana.BMC plant biology · 2026Article
- GABA enhances broad bean aluminum tolerance via reducing uptake and reinforcing lignin and (iso)flavonoid synthesis.Plant cell reports · 2026Article
- TSJT1 and glutamate is required for aluminum tolerance associated with mitochondrial pyruvate carrier 1 in Arabidopsis.Plant signaling & behavior · 2025Article
- Comprehensive review of multiomics applications and remediation of plant heavy metal toxicity.Stress biology · 2025Review
- Intrinsic and induced metabolic signatures underpin aluminum tolerance in bread wheat: a comparative metabolomics approach.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Metabolic and Nutritional Responses of Contrasting Aluminium-Tolerant Banana Genotypes Under Al Stress.Plants (Basel, Switzerland) · 2025Article
- Aluminium stress tolerance byPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- Aluminum in plant: Benefits, toxicity and tolerance mechanisms.Frontiers in plant science · 2022Review
- Identification and characterization of long noncoding RNAs involved in the aluminum stress response inFrontiers in plant science · 2022Article
- The plasma membrane-localized OsNIP1;2 mediates internal aluminum detoxification in rice.Frontiers in plant science · 2022Article
- The roles of selectivity filters in determining aluminum transport by AtNIP1;2.Plant signaling & behavior · 2021Article
- Transcriptome Analysis Revealed the Mechanisms Involved in Ultrasonic Seed Treatment-Induced Aluminum Tolerance in Peanut.Frontiers in plant science · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundIn Arabidopsis, the aluminum (Al) exclusion mechanism is mainly facilitated by ALMT1-mediated malate exudation and MATE-mediated citrate releases from the root. Recently, we have demonstrated that coordinated functioning between an ALMT1-mediated Al exclusion mechanism, via exudation of malate from the root tip, and a NIP1;2-facilitated internal detoxification mechanism, via removal of Al from the root cell wall and subsequent root-to-shoot Al translocation, plays critical roles in achieving overall Al resistance. However, the genetic relationship between ALMT1 and NIP1;2 in these processes remained unclear.
resultsThrough genetic and physiological analyses, we demonstrate that unlike ALMT1 and MATE, which function independently and additively, ALMT1 and NIP1;2 show an epistatic relationship in Al resistance. These results indicate that ALMT1 and NIP1;2 function in the same biochemical pathway, whereas ALMT1 and MATE in different ones.
conclusionThe establishment of the epistatic relationship and the coordinated functioning between the ALMT1 and NIP1;2-mediated exclusion and internal detoxification mechanisms are pivotal for achieving overall Al resistance in the non-accumulating Arabidopsis plant. We discuss and emphasize the indispensable roles of the root cell wall for the implementation of the Al exclusion mechanism and for the establishment of an epistatic relationship between the ALMT1-mediated exclusion mechanism and the NIP1;2-facilitated internal detoxification mechanism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.