ArticleCephalalgia : an international journal of headache2020
Enhanced pre-ictal cortical responsivity in migraine patients assessed by visual chirp stimulation.
Article in Cephalalgia : an international journal of headache, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Feasibility and Usability of Home-Based Visual Evoked Potential Electroencephalogram in Neurological Telemonitoring Research.Computational and structural biotechnology journal · 2026Article
- EEG Spectral Exponents and Visual Chirp Responses Mirror Anti-Seizure Medication Load in Refractory Focal Epilepsy.Annals of clinical and translational neurology · 2025Article
- Migraine with and without aura-two distinct entities? A narrative review.The journal of headache and pain · 2025Review
- Possibilities of Restoring Impaired Cognitive Functions Using Non-Invasive Activation of Neuroplasticity Mechanisms.Bulletin of experimental biology and medicine · 2025Review
- Enhancing migraine care and research through Telemedicine and telemonitoring: E-diary tracking and home EEG.Computational and structural biotechnology journal · 2025Article
- EEG Changes in Migraine-Can EEG Help to Monitor Attack Susceptibility?Brain sciences · 2024Review
- Resonance Scanning as an Efficiency Enhancer for EEG-Guided Adaptive Neurostimulation.Life (Basel, Switzerland) · 2023Article
- Bi-sinusoidal light stimulation reveals an enhanced response power and reduced phase coherence at the visual cortex in migraine.Frontiers in neurology · 2023Article
- Transcranial Magnetic Stimulation as a Therapy for Migraine: An Overview of Systematic Reviews.Journal of pain research · 2023Article
- Responsivity to light in familial hemiplegic migraine type 1 mutant mice reveals frequency-dependent enhancement of visual network excitability.The European journal of neuroscience · 2021Article
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Authors and funding
7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMigraine is associated with altered sensory processing and cortical responsivity that may contribute to susceptibility to attacks by changing brain network excitability dynamics. To gain better insight into cortical responsivity changes in migraine we subjected patients to a short series of light inputs over a broad frequency range ("chirp" stimulation), designed to uncover dynamic features of visual cortex responsivity.
methodsEEG responses to visual chirp stimulation (10-40 Hz) were measured in controls (n = 24) and patients with migraine with aura (n = 19) or migraine without aura (n = 20). Average EEG responses were assessed at (i) all EEG frequencies between 5 and 125 Hz, (ii) stimulation frequencies, and (iii) harmonic frequencies. We compared average responses in a low (10-18 Hz), medium (19-26 Hz) and high (27-40 Hz) frequency band.
resultsResponses to chirp stimulation were similar in controls and migraine subtypes. Eight measurements (n = 3 migraine with aura; n = 5 without aura) were assigned as "pre-ictal", based on reported headache within 48 hours after investigation. Pre-ictally, an increased harmonic response to 22-32 Hz stimulation (beta band) was observed (
conclusionsWe found chirp responses to be enhanced in the 48 hours prior to migraine headache onset. Visual chirp stimulation proved a simple and reliable technique with potential to detect changes in cortical responsivity associated with the onset of migraine attacks.
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