Evidence map›Paper›PMID 32187886›Full record

ArticleESC heart failure2020

Infarct-like myocarditis with coronary vasculitis and aneurysm formation caused by Epstein-Barr virus infection

Cristina Chimenti, Romina Verardo, Claudia Grande, Marco Francone, Andrea Frustaci

Open access · goldAbstract readCase Reports
In one paragraph

Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  9. Infectious factors in myocarditis: a comprehensive review of common and rare pathogens.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Review
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  16. Article
  17. Article
  18. Viral Myocarditis-From Pathophysiology to Treatment.Journal of clinical medicine · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Cristina ChimentiDepartment of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, La Sapienza University, Viale del Policlinico 155, Rome, 00161, Italy.
Romina VerardoCellular and Molecular Cardiology Lab, IRCCS L. Spallanzani, Rome, Italy.
Claudia GrandeCellular and Molecular Cardiology Lab, IRCCS L. Spallanzani, Rome, Italy.
Marco FranconeDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University, Rome, Italy.
Andrea FrustaciDepartment of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, La Sapienza University, Viale del Policlinico 155, Rome, 00161, Italy.
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITSapienza University of Rome · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

European Project ERA-CVD JTC 2016 IKDT-IGCMItalian Ministry of Health
6 · The paper itself

Abstract

Myocardial infection by Epstein-Barr virus (EBV) may manifest with inflammatory cardiomyopathy, coronary syndrome X, and rarely with infarct-like myocarditis. The aim of the report is to describe a case of myocardial EBV infection causing acute myocarditis with heart failure, necrotizing coronary vasculitis, and multiple left ventricular (LV) aneurysms. A 67-year-old woman presented with fever, chest pain, and heart failure. She underwent non-invasive cardiac studies including electrocardiography, 2D-echocardiography, cardiac magnetic resonance, hematochemical exams with Troponin T determination, and invasive studies including cardiac catheterization, coronary angiography, and LV endomyocardial biopsy. Five endomyocardial samples were processed for histology and immunohistochemistry for inflammatory cells characterization and detection of viral antigens. Two additional frozen samples were evaluated by real-time polymerase chain reaction for the presence of cardiotropic viral genomes. Routine laboratory tests revealed the presence of elevated white blood cells (17 000 10

Indexed as

AneurysmEpstein-Barr Virus InfectionsMyocarditisVasculitisAgedContrast MediaFemaleGadoliniumHerpesvirus 4, HumanHumansInfarctionContrast MediaGadoliniumAneurysmEpstein-Barr virus infectionMyocarditis

Identifiers

PMID32187886
PMCPMC7261578
OpenAlexW3011964671

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.