ArticleMedical physics2020
Modeling the impact of out-of-phase ventilation on normal lung tissue response to radiation dose.
Article in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Predicting End-of-Treatment Ventilation Response to Radiation Therapy Using Early Treatment Ventilation for Patients With Lung Cancer Treated With Photons and Protons.International journal of radiation oncology, biology, physics · 2026Article
- Weekly changes in ventilation response for photon and proton lung cancer patients during radiotherapy.medRxiv : the preprint server for health sciences · 2025Article
- Validation of CT-based ventilation and perfusion biomarkers with histopathology confirms radiation-induced pulmonary changes in a porcine model.Scientific reports · 2023Article
- Metrics of dose to highly ventilated lung are predictive of radiation-induced pneumonitis in lung cancer patients.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2023Article
- Quantifying robustness of CT-ventilation biomarkers to image noise.Frontiers in physiology · 2023Article
- CT-derived vessel segmentation for analysis of post-radiation therapy changes in vasculature and perfusion.Frontiers in physiology · 2022Article
- Radiation-induced airway changes and downstream ventilation decline in a swine model.Biomedical physics & engineering express · 2021Article
- Geodesic density regression for correcting 4DCT pulmonary respiratory motion artifacts.Medical image analysis · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo create a dose-response model that predicts lung ventilation change following radiation therapy, and examine the effects of out-of-phase ventilation.
methodsThe dose-response model was built using 27 human subjects who underwent radiation therapy (RT) from an IRB-approved trial. For each four-dimensional computed tomography, two ventilation maps were created by calculating the N-phase local expansion ratio (LER
resultsFor voxels receiving 20 Gy or greater, there was a significant increase from 52% to 59% (P = 0.03) in the gamma pass rates of the LER
conclusionsThe LER
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.