ArticleRevista da Sociedade Brasileira de Medicina Tropical2020
Absence of mutations associated with resistance to benzimidazole in the beta-tubulin gene of Ascaris suum.
Article in Revista da Sociedade Brasileira de Medicina Tropical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Evaluating beta-tubulin variants as predictors of benzimidazole resistance across Caenorhabditis nematodes.PLoS pathogens · 2026Article
- Biodigesters for Sustainable Food Waste Management.International journal of environmental research and public health · 2025Review
- Worldwide absence of canonical benzimidazole resistance-associated mutations within β-tubulin genes from Ascaris.Parasites & vectors · 2024Article
- The equine ascarids: resuscitating historic model organisms for modern purposes.Parasitology research · 2022Review
- Development of allele-specific PCR methodology (AS-PCR) to screening A. lumbricoides and A. suum.Parasitology research · 2022Article
- Characterization of the β-tubulin gene family in Ascaris lumbricoides and Ascaris suum and its implication for the molecular detection of benzimidazole resistance.PLoS neglected tropical diseases · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBenzimidazoles are commonly used for the control of veterinary nematodes. Resistance to benzimidazoles has been associated with three single nucleotide polymorphisms in the β-tubulin gene of common nematodes. However, these mutations are infrequent in the genus Ascaris spp.
methodsIn order to determine mutations associated with benzimidazole resistance in Ascaris suum, worms were collected from slaughtered pigs and a partial region of the β-tubulin gene was sequenced.
resultsAll parasites showed the wildtype genotype for codons 167, 198, and 200 of the β-tubulin gene.
conclusionsThis is the first report of genetic sequences associated with benzimidazole resistance in A. suum.
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