ArticleMedical care2020
Strategy Configurations Directly Linked to Higher Hepatitis C Virus Treatment Starts: An Applied Use of Configurational Comparative Methods.
Article in Medical care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
70 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Implementation strategies to increase tobacco treatment in mental health settings: a systematic review.BMC psychiatry · 2025Pooled it
- Application of the Expert Recommendations for Implementing Change (ERIC) compilation of strategies to health intervention implementation in low- and middle-income countries: a systematic review.Implementation science : IS · 2023Pooled it
- Factors that distinguish opioid withdrawal during induction with buprenorphine microdosing: a configurational analysis.Addiction science & clinical practice · 2022Pooled it
- Difference-Makers for Robust Implementation of a Nursing Home Advance Care Planning Embedded Pragmatic Clinical Trial.Journal of the American Geriatrics Society · 2026Trial
- Opioid treatment program-integrated facilitated telemedicine for hepatitis C treatment: a hybrid effectiveness-implementation analysis.BMC complementary medicine and therapies · 2025Trial
- The difference-making role of staff support in implementing nurse care management for opioid use disorder treatment: A configurational analysis.Journal of substance use and addiction treatment · 2025Trial
- Factors facilitating the implementation of a clinical decision support system in primary care practices: a fuzzy set qualitative comparative analysis.BMC health services research · 2023Trial
- Defining optimal implementation packages for delivering community-wide mass drug administration for soil-transmitted helminths with high coverage.BMC health services research · 2022Trial
- A cluster randomized stepped-wedge trial to de-implement unnecessary post-operative antibiotics in children: the optimizing perioperative antibiotic in children (OPerAtiC) trial.Implementation science : IS · 2021Trial
- How local prevention efforts and state regulations intersect to reduce fatal shootings: a configurational analysis of firearm policies in the United States.Journal of public health policy · 2026Article
- Factor selection in configurational comparative analysis - guidance for implementation researchers.Implementation science communications · 2026Article
- Community organization capacity and barriers to mental health promotion efforts: a configurational analysis.BMC public health · 2026Article
- Employers' utilization of and collaboration with occupational health services in preventive occupational health and safety management.Scandinavian journal of work, environment & health · 2026Article
- Difference-making factors in implementing a quality improvement program for sleep apnea in stroke/TIA patients.Implementation science communications · 2026Article
- How segregation, low birth weight, unemployment, and violence link to low life expectancy in Chicago.Health affairs scholar · 2026Article
- Organizational readiness for implementing infection control in European hospitals: insights from Coincidence Analysis.Implementation science communications · 2026Article
- Difference-making pathways to implementing systematic, partial, or no data collection of sexual orientation and gender identity in oncology settings: a coincidence analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Barriers to Same-Day Pre-exposure Prophylaxis (PrEP) Implementation in Federally Funded HIV Clinics Within High-Burden Areas of the U.S.: A Coincidence Analysis.AIDS and behavior · 2026Article
- Real-world quantification of implementation dose across twenty-five implementation instances.Implementation science communications · 2025Article
- Explaining site-level fidelity within a national initiative to implement a VA patient safety guidebook: the difference-making role of networks & communications.Implementation science communications · 2025Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
backgroundThe Department of Veterans Affairs (VA) cares for more patients with hepatitis C virus (HCV) than any other US health care system. We tracked the implementation strategies that VA sites used to implement highly effective new treatments for HCV with the aim of uncovering how combinations of implementation strategies influenced the uptake of the HCV treatment innovation. We applied Configurational Comparative Methods (CCMs) to uncover causal dependencies and identify difference-making strategy configurations, and to distinguish higher from lower HCV treating sites.
methodsWe surveyed providers to assess VA sites' use of 73 implementation strategies to promote HCV treatment in the fiscal year 2015. CCMs were used to identify strategy configurations that uniquely distinguished higher HCV from lower HCV treating sites.
resultsFrom the 73 possible implementation strategies, CCMs identified 5 distinct strategy configurations, or "solution paths." These were comprised of 10 individual strategies that collectively explained 80% of the sites with higher HCV treatment starts with 100% consistency. Using any one of the following 5 solution paths was sufficient to produce higher treatment starts: (1) technical assistance; (2) engaging in a learning collaborative AND designating leaders; (3) site visits AND outreach to patients to promote uptake and adherence; (4) developing resource sharing agreements AND an implementation blueprint; OR (5) creating new clinical teams AND sharing quality improvement knowledge with other sites AND engaging patients. There was equifinality in that the presence of any one of the 5 solution paths was sufficient for higher treatment starts.
conclusionsFive strategy configurations distinguished higher HCV from lower HCV treating sites with 100% consistency. CCMs represent a methodological advancement that can help inform high-yield implementation strategy selection and increase the efficiency and effectiveness of future implementation efforts.
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