Evidence map›Paper›PMID 32186970›Full record

ArticleMolecular biology of the cell2020

Mechanistic insights into actin-driven polarity site movement in yeast.

Debraj Ghose, Daniel Lew

Open access · bronzeAbstract read
In one paragraph

Article in Molecular biology of the cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Patterning of the cell cortex by Rho GTPases.Nature reviews. Molecular cell biology · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Orientation of Cell Polarity by Chemical Gradients.Annual review of biophysics · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Chemotactic movement of a polarity site enables yeast cells to find their mates.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Debraj GhoseComputational Biology and Bioinformatics, Duke University Medical Center, Durham, NC 27710.
Daniel LewDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710.
Duke Medical Center · USDuke University · US

Funding

Studies on cell polarity, chemotropism, and cell cycle controlR35GM122488 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI DANIEL J LEW · 2017 to 2026
$6.9M
NIGMS NIH HHS R35 GM122488
6 · The paper itself

Abstract

Directed cell growth or migration are critical for the development and function of many eukaryotic cells. These cells develop a dynamic "front" (also called "polarity site") that can change direction. Polarity establishment involves autocatalytic accumulation of polarity regulators, including the conserved Rho-family GTPase Cdc42, but the mechanisms underlying polarity reorientation remain poorly understood. The tractable model yeast,

Indexed as

Cell PolarityActinscdc42 GTP-Binding Protein, Saccharomyces cerevisiaeCell MembraneModels, BiologicalMovementSaccharomyces cerevisiaeSecretory VesiclesActinscdc42 GTP-Binding Protein, Saccharomyces cerevisiae

Identifiers

PMID32186970
PMCPMC7346724
OpenAlexW3012129457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.