Evidence map›Paper›PMID 32186897›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2020

Exploration of cardiometabolic and developmental significance of angiotensinogen expression by cells expressing the leptin receptor or agouti-related peptide.

Sarah A Sapouckey, Lisa L Morselli, Guorui Deng, Chetan N Patil, Kirthikaa Balapattabi, Vanessa Oliveira, Kristin E Claflin, Javier Gomez, Nicole A Pearson, Matthew J Potthoff and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Angiotensin ATiScience · 2025
    Article
  2. Article
  3. Article
  4. Melanocortin MCPhysiological genomics · 2022
    Article
  5. Article
  6. Review
  7. β-Arrestin-Biased Agonist Targeting the Brain ATHypertension (Dallas, Tex. : 1979) · 2021
    Article
  8. American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Sarah A SapouckeyDepartment of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.
Lisa L MorselliDivision of Endocrinology, Department of Internal Medicine, University of Iowa, Iowa City, Iowa.
Guorui DengDepartment of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.
Chetan N PatilDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Kirthikaa BalapattabiDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0001-5455-6037
Vanessa OliveiraDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Kristin E ClaflinDepartment of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.
Javier GomezDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Nicole A PearsonDepartment of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.
Matthew J PotthoffDepartment of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa.
Katherine N Gibson-CorleyFraternal Order of Eagles' Diabetes Research Center, University of Iowa, Iowa City, Iowa.
Curt D SigmundDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0002-1453-0921
Justin L GrobeDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0001-9737-0873
University of Iowa · USMedical College of Wisconsin · US

Funding

Role of the brain Renin-Angiotensin Sys. in Cardiovas and Metabolic RegulationP01HL084207 · NHLBI · UNIVERSITY OF IOWA · PI GROBE, JUSTIN L · 2007 to 2022
$30.2M
Multidisciplinary Lung Research Career Development ProgramT32HL007638 · NHLBI · UNIVERSITY OF IOWA · PI WELSH, MICHAEL J., ZABNER, JOSEPH · 1986 to 2020
$16.9M
Regulation of Metabolism by FGF21R01DK106104 · NIDDK · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Matthew Joseph Potthoff · 2015 to 2026
$6.2M
PPARG-dependent Mechanisms Control Endothelial-Smooth Muscle Coordination, Arterial Pressure, Vasomotor Function and Arterial StiffnessR35HL144807 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI SIGMUND, CURT DANIEL · 2019 to 2024
$5.5M
Interaction between leptin and angiotensin in the pathogenesis of obesity-hypertensionR01HL134850 · NHLBI · UNIVERSITY OF IOWA · PI Justin L Grobe · 2017 to 2026
$4.4M
Request for Funds to Purchase a Replacement Laser Scanning Confocal MicroscopeS10RR025439 · NCRR · UNIVERSITY OF IOWA · PI ZABNER, JOSEPH · 2009 to 2009
$500k
NCRR NIH HHS S10 RR025439NHLBI NIH HHS P01 HL084207NHLBI NIH HHS R01 HL134850NHLBI NIH HHS R35 HL144807NHLBI NIH HHS T32 HL007638NIDDK NIH HHS R01 DK106104
6 · The paper itself

Abstract

Angiotensin II (ANG II)

Indexed as

Energy MetabolismAdrenal GlandsAgouti-Related ProteinAngiotensinogenAnimalsArcuate Nucleus of HypothalamusAutocrine CommunicationFemaleGene Expression Regulation, DevelopmentalKidneyMaleMice, KnockoutMyocardiumParacrine CommunicationReceptors, LeptinSerum AlbuminAgouti-Related ProteinAgrp protein, mouseAgt protein, mouseAngiotensinogenleptin receptor, mouseReceptors, LeptinSerum Albuminadrenal glandagouti-related peptideangiotensinogendevelopmentleptin

Identifiers

PMID32186897
PMCPMC7272763
OpenAlexW3010831855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.