Evidence map›Paper›PMID 32185880›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

Pain expectancy, prevalence, severity, and patterns following donor nephrectomy: Findings from the KDOC Study.

Aaron Fleishman, Khalid Khwaja, Jesse D Schold, Carly D Comer, Paul Morrissey, James Whiting, John Vella, Liise K Kayler, Daniel Katz, Jody Jones and 5 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07396753 (The Effects of Transversalis Fascia Plane Block on Opioid Consumption in Patients Undergoing Hand-Assisted Laparoscopic Donor Nephrectomy), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07396753 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effects of Transversalis Fascia Plane Block on Opioid Consumption in Patients Undergoing Hand-Assisted Laparoscopic Donor Nephrectomy: A Randomized Controlled Prospective Study

TypeinterventionalSponsorKoç UniversityRan2025 to 2026Enrolled50ConditionsPostoperative Pain, Analgesics, Opioid, Pain Management, Anesthesia RegionalArmsUltrasound-guided transversalis fascia plane block
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Aaron FleishmanThe Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Khalid KhwajaThe Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Jesse D ScholdDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.
Carly D ComerThe Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Paul MorrisseyTransplant Center, Rhode Island Hospital, Providence, RI, USA.
James WhitingMaine Transplant Center, Maine Medical Center, Portland, ME, USA.
John VellaMaine Transplant Center, Maine Medical Center, Portland, ME, USA.
Liise K KaylerMontefiore Einstein Center for Transplantation, Bronx, NY, USA.
Daniel KatzOrgan Transplantation Program, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Jody JonesOrgan Transplantation Program, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Bruce KaplanBaylor Scott and White Health, Temple, TX, USA.
Martha PavlakisThe Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Didier A MandelbrotDepartment of Medicine, University of Wisconsin, Madison, WI, USA.
James R RodrigueThe Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID 0000-0001-5589-4919
KDOC Study Group
Beth Israel Deaconess Medical Center · USMaine Medical Center · USUniversity of Iowa Hospitals and Clinics · USAlbert Einstein College of Medicine · USBaylor Scott & White Health · USCleveland Clinic · USProvidence College · USUniversity of Wisconsin–Madison · US

Funding

Kidney Donor Outcomes Cohort (KDOC) StudyR01DK085185 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MANDELBROT, DIDIER A, RODRIGUE, JAMES R · 2011 to 2014
$2.8M
NIDDK NIH HHS R01 DK085185
6 · The paper itself

Abstract

Postoperative pain is an outcome of importance to potential living kidney donors (LKDs). We prospectively characterized the prevalence, severity, and patterns of acute or chronic postoperative pain in 193 LKDs at six transplant programs. Three pain measurements were obtained from donors on postoperative Day (POD) 1, 3, 7, 14, 21, 28, 35, 41, 49, and 56. The median pain rating total was highest on POD1 and declined from each assessment to the next until reaching a median pain-free score of 0 on POD49. In generalized linear mixed-model analysis, the mean pain score decreased at each pain assessment compared to the POD3 assessment. Pre-donation history of mood disorder (adjusted ratio of means [95% confidence interval (CI)]: 1.40 [0.99, 1.98]), reporting "severe" on any POD1 pain descriptors (adjusted ratio of means [95% CI]: 1.47 [1.12, 1.93]) and open nephrectomy (adjusted ratio of means [95% CI]: 2.61 [1.03, 6.62]) were associated with higher pain scores across time. Of the 179 LKDs who completed the final pain assessment, 74 (41%) met criteria for chronic postsurgical pain (CPSP), that is, any donation-related pain on POD56. Study findings have potential implications for LKD education, surgical consent, postdonation care, and outcome measurements.

Indexed as

Kidney TransplantationFollow-Up StudiesHumansLiving DonorsNephrectomyPostoperative PainPrevalenceanesthesia/pain managementclinical research/practicedonors and donationdonors and donation: donor follow-updonors and donation: livinghealth services and outcomes researchkidney transplantation:living donorkidney transplantation/nephrologyquality of life (QOL)

Identifiers

PMID32185880
PMCPMC7483675
OpenAlexW3012209008

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.