Evidence map›Paper›PMID 32185701›Full record

ArticleJournal of ultrasound2020

Assessment of thyroid gland elasticity with shear-wave elastography in Hashimoto's thyroiditis patients.

Turgay Kara, Fatih Ateş, Mehmet Sedat Durmaz, Nesibe Akyürek, Funda Gökgöz Durmaz, Bora Özbakır, Mehmet Öztürk

Open access · greenAbstract read
In one paragraph

Article in Journal of ultrasound, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

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  11. Ultrasound Elastography in Children.Children (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Turgay KaraDepartment of Radiology, Medicine Faculty, Sutçu Imam University, Kahramanmaraş, Türkiye. trgykr@gmail.com.tr.ORCID http://orcid.org/0000-0001-8448-9066
Fatih AteşDepartment of Radiology, Konya Training and Research Hospital, Health Sciences University, Konya, Turkey.ORCID http://orcid.org/0000-0002-2693-4616
Mehmet Sedat DurmazDepartment of Radiology, Medicine Faculty, Selçuk University, Konya, Turkey.ORCID http://orcid.org/0000-0002-1340-2477
Nesibe AkyürekDepartment of Pediatric Endocrinology, Konya Training and Research Hospital, Health Sciences University, Konya, Turkey.ORCID http://orcid.org/0000-0003-3443-0829
Funda Gökgöz DurmazKaratay Community Health Center Family Medicine, Konya, Turkey.ORCID http://orcid.org/0000-0003-3043-5809
Bora ÖzbakırDepartment of Radiology, Gynecology-Obstetrics and Pediatrics Hospital, Isparta, Turkey.ORCID http://orcid.org/0000-0002-1909-0478
Mehmet ÖztürkDepartment of Radiology, Medicine Faculty, Selçuk University, Konya, Turkey.ORCID http://orcid.org/0000-0002-2396-1096
Konya Food and Agriculture University · TRSelçuk University · TRIsparta University of Applied Sciences · TRKahramanmaraş Sütçü İmam University · TRKTO Karatay University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to investigate the use and effectiveness of Shear-Wave Elastography (SWE) in Hashimoto's Thyroiditis (HT) diagnosis and compare the SWE values in HT patients with asymptomatic volunteers.

methodsThe thyroid gland parenchyma of 74 patients whose clinical and laboratory findings and ultrasonography (US) features were indicative of HT and 75 healthy, asymptomatic participants with normal laboratory values were examined using SWE. Their thyroid parenchymal echoes and thyroid gland volume were measured using B-mode US examination. Elastographic measurements were made by plotting the boundaries of thyroid gland by hand, using Free Region of Interest (ROI). The quantitative SWE values [meters/second (m/s) and kilopascal (kPa)] were compared betweent the patients and the controls. The correlation analyses between the SWE measurements and the autoantibodies [Anti-thyroid peroxidase antibody (TPOAbs) and anti-thyroglobulin antibodies (TgAbs)], thyroid-stimulating hormone (TSH), freetriiodothyronine (fT3), free-thyroxine (fT4), and thyroglobulin levels were performed.

resultsThe mean thyroid SWE measurement values of HT group were significantly higher than the asymptomatic group (p < 0.001). This study proposes 29.45 kPa or 2.77 m/s as a sensitive-spesific cut-off value for HT. We revealed significant positive association between SWE values and TgAb levels, gland volume, TgAb, TPOAb levels, and a significant negative association between SWE and echogenicity (p < 0.001).

conclusionIn the assessment of HT, SWE is a highly sensitive imaging method to estimate the degree of fibrosis and to provide objective numerical values.

Indexed as

Elasticity Imaging TechniquesAdolescentAdultAutoantibodiesCase-Control StudiesChildFemaleHashimoto DiseaseHumansMaleMiddle AgedROC CurveThyroid GlandYoung AdultAutoantibodiesFree ROIHashimoto’s thyroiditisShear wave elastographyUltrasonography

Identifiers

PMID32185701
PMCPMC7588574
OpenAlexW3011046912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.