Evidence map›Paper›PMID 32185578›Full record

ArticleJournal of clinical immunology2020

The IL1RN Mutation Creating the Most-Upstream Premature Stop Codon Is Hypomorphic Because of a Reinitiation of Translation.

Kunihiko Moriya, Saori Kadowaki, Tomohiro Nakano, Sanem E Akarcan, Necil Kutukculer, Guzide Aksu, Yoji Sasahara, Shigeo Kure, Hidenori Ohnishi, Jean-Laurent Casanova and 2 more

Erratum issuedAbstract readLetter
PubMed Publisher
In one paragraph

Article in Journal of clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Kunihiko MoriyaLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Paris, France. kunihiko.moriya.a3@tohoku.ac.jp.
Saori KadowakiDepartment of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.
Tomohiro NakanoDepartment of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Sanem E AkarcanDepartment of Pediatric Immunology and Rheumatology, Ege University Faculty of Medicine, Izmir, Turkey.
Necil KutukculerDepartment of Pediatric Immunology and Rheumatology, Ege University Faculty of Medicine, Izmir, Turkey.
Guzide AksuDepartment of Pediatric Immunology and Rheumatology, Ege University Faculty of Medicine, Izmir, Turkey.
Yoji SasaharaDepartment of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Shigeo KureDepartment of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hidenori OhnishiDepartment of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan. ohnishih@gifu-u.ac.jp.
Jean-Laurent CasanovaLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Paris, France.
Anne PuelLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Paris, France.
Toshiyuki FukaoDepartment of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Codon, NonsenseHEK293 CellsHereditary Autoinflammatory DiseasesHumansInterleukin 1 Receptor Antagonist ProteinMutationPeptide Chain Initiation, TranslationalCodon, NonsenseIL1RN protein, humanInterleukin 1 Receptor Antagonist Protein

Identifiers

PMID32185578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.